Concepedia

Mutation Generation During Replication

Mutation Generation During Replication is a virological mechanism characterized by the introduction of genetic alterations in viral genomes during the process of replication, distinguished from other mutational processes by its direct dependence on viral polymerase fidelity and replication dynamics.

77

Publications

4.7K

Citations

307

Authors

131

Institutions

Publications per year

2017–2026

4

Parents

Publications

77

Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing

Lance D. Eckerle, Michelle M. Becker, Rebecca Halpin et al. · PLoS Pathogens · 2010 · 525 citations · Full text

, , +17

Specificity and Mechanism of Error-prone Replication by Human Immunodeficiency Virus-1 Reverse Transcriptase

Katarzyna Bębenek, John Abbotts, John D. Roberts et al. · Journal of Biological Chemistry · 1989 · 314 citations · Full text

, , +17

Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions.

Vinay K. Pathak, Howard M. Temin · Proceedings of the National Academy of Sciences · 1990 · 213 citations

, , +14

The nature of mutations induced by replication–transcription collisions

Tejas Sankar, Brigitta Wastuwidyaningtyas, Yuexin Dong et al. · Nature · 2016 · 147 citations · Full text

, , +10

Coxsackievirus B3 mutator strains are attenuated in vivo

Nina F. Gnädig, Stéphanie Beaucourt, Grace Campagnola et al. · Proceedings of the National Academy of Sciences · 2012 · 139 citations · Full text

, , +16

1–5 of 77

Authors

307

  1. JP
    Joseph P. Dougherty

    Johnson University, United States

    4 publications · 253 citations

    4

    h-index

  2. LA
    Lawrence A. Loeb

    University of Washington, United States

    3 publications · 222 citations

    3

    h-index

  3. YR
    Yacov Ron

    Johnson University, United States

    3 publications · 184 citations

    3

    h-index

  4. AT
    Antonito T. Panganiban

    University of Wisconsin–Madison, United States

    3 publications · 88 citations

    3

    h-index

  5. ED
    Esteban Domingo

    Centro de Biología Molecular Severo Ochoa, Spain

    3 publications · 102 citations

    3

    h-index

1–5 of 307

Institutions

131

  1. University of Wisconsin–Madison

    Madison, United States

    6 h-index

    14 publications

    1.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    14 publications

    886 citations

  3. National Institute of Environmental Health Sciences

    Durham, United States

    4 h-index

    9 publications

    1.1K citations

  4. Centro de Biología Molecular Severo Ochoa

    Madrid, Spain

    3 h-index

    10 publications

    365 citations

  5. Johnson University

    Knoxville, United States

    3 h-index

    12 publications

    707 citations

  6. Institut Pasteur

    Paris, France

    3 h-index

    14 publications

    1.2K citations

  7. National Cancer Institute

    Bethesda, United States

    3 h-index

    10 publications

    704 citations

  8. Rutgers, The State University of New Jersey

    New Brunswick, United States

    3 h-index

    9 publications

    701 citations

1–8 of 131

Venues

  1. Journal of Virology

    JVI · 13 publications · 667 citations

    12

    h-index

  2. Virology

    12 publications · 455 citations

    11

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 721 citations

    6

    h-index

  4. Journal of Biological Chemistry

    JBC · 5 publications · 573 citations

    5

    h-index

  5. PLoS Pathogens

    3 publications · 597 citations

    3

    h-index

1–5