Concepedia

Mutation Burden Estimation

Mutation Burden Estimation is a computational method in single-cell variant analysis that quantifies the total number of somatic mutations per cell, distinguishing itself from alternative genomic quantification approaches by enabling cell-specific assessment of mutational load within heterogeneous tumor populations.

179

Publications

9.9K

Citations

2.2K

Authors

635

Institutions

Publications per year

2017–2026

154

Parents

Publications

179

Association of Patient Characteristics and Tumor Genomics With Clinical Outcomes Among Patients With Non–Small Cell Lung Cancer Using a Clinicogenomic Database

Gaurav Singal, Peter G. Miller, Vineeta Agarwala et al. · JAMA · 2019 · 565 citations · Full text

, , +16

RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues

Keren Yizhak, François Aguet, Jaegil Kim et al. · Science · 2019 · 516 citations · Full text

, , +17

Establishing guidelines to harmonize tumor mutational burden (TMB): in silico assessment of variation in TMB quantification across diagnostic platforms: phase I of the Friends of Cancer Research TMB Harmonization Project

Diana M. Merino, Lisa M. McShane, David Fabrizio et al. · Journal for ImmunoTherapy of Cancer · 2020 · 506 citations · Full text

, , +17

Prevalence and mutational determinants of high tumor mutation burden in breast cancer

Romualdo Barroso‐Sousa, Esha Jain, Ofir Cohen et al. · Annals of Oncology · 2020 · 357 citations

, , +16

Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

Tianyun Wang, Kendra Hoekzema, Davide Vecchio et al. · Nature Communications · 2020 · 215 citations · Full text

, , +17

1–5 of 179

Authors

2.2K

  1. JS
    Jeffrey S. Ross

    Foundation Medicine (United States)

    8 publications · 434 citations

    8

    h-index

  2. AS
    Albrecht Stenzinger

    Heidelberg University, Germany

    7 publications · 1.2K citations

    7

    h-index

  3. DF
    David Fabrizio

    Foundation Medicine (United States)

    7 publications · 953 citations

    7

    h-index

  4. GM
    Garrett M. Frampton

    Foundation Medicine (United States)

    6 publications · 903 citations

    6

    h-index

  5. JB
    Jan Budczies

    Charité - Universitätsmedizin Berlin, Germany

    5 publications · 536 citations

    5

    h-index

1–5 of 2.2K

Institutions

635

  1. Foundation Medicine (United States)

    Cambridge, United States

    12 h-index

    106 publications

    13.1K citations

  2. Memorial Sloan Kettering Cancer Center

    New York, United States

    10 h-index

    64 publications

    2.9K citations

  3. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    9 h-index

    58 publications

    3.3K citations

  4. University Hospital Heidelberg

    Heidelberg, Germany

    8 h-index

    79 publications

    8.9K citations

  5. Dana-Farber Cancer Institute

    Boston, United States

    8 h-index

    37 publications

    4.5K citations

  6. Heidelberg University

    Heidelberg, Germany

    8 h-index

    85 publications

    9.6K citations

  7. Sun Yat-sen University

    Guangzhou, China

    8 h-index

    34 publications

    903 citations

  8. The University of Texas MD Anderson Cancer Center

    Houston, United States

    6 h-index

    35 publications

    1.8K citations

1–8 of 635

Venues

  1. Journal of Clinical Oncology

    11 publications · 374 citations

    11

    h-index

  2. Frontiers in Oncology

    10 publications · 406 citations

    10

    h-index

  3. Journal of Thoracic Oncology

    7 publications · 685 citations

    7

    h-index

  4. Lung Cancer

    5 publications · 138 citations

    5

    h-index

  5. Scientific Reports

    5 publications · 151 citations

    5

    h-index

1–5