Multiprotein Signalosomes
Multiprotein Signalosomes is a dynamic macromolecular complex that functions as a centralized signaling hub by integrating multiple signal transduction proteins to coordinate specific cellular responses through spatially and temporally regulated protein-protein interactions.
41
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2.9K
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218
Authors
95
Institutions
Publications per year
2017–2026
6
41
Crystal structure of the human COP9 signalosome
Gondichatnahalli M. Lingaraju, R.D. Bunker, Simone Cavadini et al. · Nature · 2014 · 231 citations
Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome
Stefan Uhle, Ohad Medalia, Richard T. Waldron et al. · The EMBO Journal · 2003 · 202 citations · Full text
The COP9 signalosome is essential for development of Drosophila melanogaster
Shiri Freilich, Efrat Oron, Ya'ara Kapp et al. · Current Biology · 1999 · 154 citations · Full text
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95

Tel Aviv University
Tel Aviv, Israel
4 h-index
26 publications
1.9K citations
Max Planck Institute of Biochemistry
Martinsried, Germany
3 h-index
3 publications
322 citations
Charité - Universitätsmedizin Berlin
Berlin, Germany
3 h-index
12 publications
662 citations

Centre National de la Recherche Scientifique
Paris, France
3 h-index
18 publications
1.5K citations
Harvard University
Cambridge, United States
2 h-index
3 publications
63 citations

MRC Laboratory of Molecular Biology
Cambridge, United Kingdom
2 h-index
11 publications
616 citations
Inserm
Paris, France
2 h-index
8 publications
768 citations
Dana-Farber Cancer Institute
Boston, United States
2 h-index
4 publications
219 citations
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JBC · 4 publications · 282 citations
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3 publications · 130 citations
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JMB · 3 publications · 241 citations
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2 publications · 229 citations
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JCCI · 2 publications · 76 citations
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