Concepedia

Multiple Dosing Models

Multiple Dosing Models is a pharmacokinetic modeling framework that characterizes the repeated administration of oral drug doses over time to predict steady-state concentrations, accumulation, and temporal drug exposure profiles in contrast to single-dose approaches.

88

Publications

3.9K

Citations

426

Authors

154

Institutions

Publications per year

2017–2026

11

Variants

Multiple-dosing Models

Parents

Publications

88

Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939—an oral, direct Factor Xa inhibitor—after multiple dosing in healthy male subjects

Dagmar Kubitza, Michael Becka, Georg Wensing et al. · European Journal of Clinical Pharmacology · 2005 · 648 citations

, , +5

Prediction of multidimensional drug dose responses based on measurements of drug pairs

Anat Zimmer, Itay Katzir, E. Dekel et al. · Proceedings of the National Academy of Sciences · 2016 · 169 citations · Full text

, , +13

Gentamicin disposition and tissue accumulation on multiple dosing

Jerome J. Schentag, William J. Jusko, John W. Vance et al. · Journal of Pharmacokinetics and Biopharmaceutics · 1977 · 141 citations

, , +9

Pharmacokinetics and Pharmacodynamics of Exenatide Extended-Release After Single and Multiple Dosing

Mark Fineman, Shawn Flanagan, Kristin Taylor et al. · Clinical Pharmacokinetics · 2010 · 135 citations

, , +10

The bioavailability and pharmacokinetics of glucosamine hydrochloride and low molecular weight chondroitin sulfate after single and multiple doses to beagle dogs

Abi Adebowale, Jianpin Du, Zhonming Liang et al. · Biopharmaceutics & Drug Disposition · 2002 · 124 citations

, , +11

1–5 of 88

Authors

426

  1. DJ
    David J. Greenblatt

    Tufts University, United States

    3 publications · 103 citations

    3

    h-index

  2. HR
    Hermann R. Ochs

    Tufts Medical Center, United States

    2 publications · 67 citations

    2

    h-index

  3. WJ
    William J. Jusko

    University at Buffalo, State University of New York, United States

    2 publications · 162 citations

    2

    h-index

  4. LZ
    Leslie Z. Benet

    University of California, San Francisco, United States

    2 publications · 125 citations

    2

    h-index

  5. TM
    Travis Mickle

    KemPharm (United States), United States

    1 publications · 17 citations

    1

    h-index

1–5 of 426

Institutions

154

  1. Center for Drug Evaluation and Research

    Silver Spring, United States

    4 h-index

    11 publications

    635 citations

  2. University of California, San Francisco

    San Francisco, United States

    3 h-index

    6 publications

    280 citations

  3. Roche (Switzerland)

    Basel, Switzerland

    3 h-index

    13 publications

    473 citations

  4. University at Buffalo, State University of New York

    Buffalo, United States

    3 h-index

    10 publications

    958 citations

  5. Eli Lilly (United States)

    Indianapolis, United States

    3 h-index

    7 publications

    446 citations

  6. The University of Sydney

    Sydney, Australia

    3 h-index

    11 publications

    279 citations

  7. University of Washington

    Seattle, United States

    2 h-index

    5 publications

    378 citations

  8. W.E. Upjohn Institute for Employment Research

    Kalamazoo, United States

    2 h-index

    3 publications

    54 citations

1–8 of 154

Venues

  1. 5

    h-index

  2. Journal of Pharmaceutical Sciences

    5 publications · 124 citations

    5

    h-index

  3. European Journal of Clinical Pharmacology

    5 publications · 747 citations

    5

    h-index

  4. Clinical Pharmacology & Therapeutics

    CPT · 4 publications · 229 citations

    4

    h-index

  5. PubMed

    Repository · 4 publications · 144 citations

    4

    h-index

1–5