Concepedia

Multi-omics-guided Strain Design

Multi-Omics-Guided Strain Design is a systematic approach in metabolic engineering that integrates genomic, transcriptomic, proteomic, and metabolomic data to identify targeted genetic modifications for optimizing microbial cell factories, distinguishing itself from conventional strain design methods through its holistic, data-driven utilization of multiple layers of biological information.

9

Publications

238

Citations

84

Authors

34

Institutions

Publications per year

2017–2026

7

Parents

Publications

9

Omics-driven identification and elimination of valerolactam catabolism in Pseudomonas putida KT2440 for increased product titer

Mitchell G. Thompson, Luis E. Valencia, Jacquelyn M. Blake-Hedges et al. · Metabolic Engineering Communications · 2019 · 38 citations · Full text

, , +17

Approaches to Computational Strain Design in the Multiomics Era

Peter C. St. John, Yannick J. Bomble · Frontiers in Microbiology · 2019 · 35 citations · Full text

, , +17

Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea

Katarina Karničar, Igor Drobnak, Marko Petek et al. · Microbial Cell Factories · 2016 · 33 citations · Full text

, , +17

Development of a Genome-Scale Metabolic Model of Clostridium thermocellum and Its Applications for Integration of Multi-Omics Datasets and Computational Strain Design

Sergio Garcia, R. Adam Thompson, Richard J. Giannone et al. · Frontiers in Bioengineering and Biotechnology · 2020 · 27 citations · Full text

, , +17

Multiomics Data Collection, Visualization, and Utilization for Guiding Metabolic Engineering

Somtirtha Roy, Tijana Radivojević, Mark Forrer et al. · Frontiers in Bioengineering and Biotechnology · 2021 · 26 citations · Full text

, , +13

1–5 of 9

Authors

84

  1. JK
    Joonhoon Kim

    Pacific Northwest National Laboratory, United States

    2 publications · 48 citations

    2

    h-index

  2. NJ
    Nathan J. Hillson

    Joint BioEnergy Institute, United States

    2 publications · 48 citations

    2

    h-index

  3. TL
    Teresa Lemmon

    Pacific Northwest National Laboratory, United States

    1 publications · 22 citations

    1

    h-index

  4. GB
    Gwénäelle Bestel‐Corre

    Centre National de la Recherche Scientifique, France

    1 publications · 16 citations

    1

    h-index

  5. JD
    Jay D. Keasling

    University of California, Berkeley, United States

    1 publications · 38 citations

    1

    h-index

1–5 of 84

Institutions

34

  1. Joint BioEnergy Institute

    Emeryville, United States

    3 h-index

    23 publications

    746 citations

  2. Lawrence Berkeley National Laboratory

    Berkeley, United States

    3 h-index

    24 publications

    784 citations

  3. Pacific Northwest National Laboratory

    Richland, United States

    2 h-index

    19 publications

    422 citations

  4. Umaru Musa Yar'adua University

    Katsina, Nigeria

    1 h-index

    2 publications

    42 citations

  5. Shenzhen Institutes of Advanced Technology

    Shenzhen, China

    1 h-index

    1 publications

    38 citations

  6. University of Tennessee at Knoxville

    Knoxville, United States

    1 h-index

    3 publications

    81 citations

  7. Tecnológico de Monterrey

    Monterrey, Mexico

    1 h-index

    1 publications

    38 citations

  8. Acies Bio (Slovenia)

    Ljubljana, Slovenia

    1 h-index

    7 publications

    231 citations

1–8 of 34

Venues

  1. Frontiers in Bioengineering and Biotechnology

    3 publications · 75 citations

    3

    h-index

  2. Bioresource Technology

    1 publications · 20 citations

    1

    h-index

  3. UMYU Journal of Microbiology Research (UJMR)

    1 publications · 21 citations

    1

    h-index

  4. Metabolic Engineering Communications

    1 publications · 38 citations

    1

    h-index

  5. Molecular & Cellular Proteomics

    MCP · 1 publications · 16 citations

    1

    h-index

1–5