Concepedia

Multi-endpoint Dose-response Modeling

Multi-Endpoint Dose-Response Modeling is a statistical modeling framework that characterizes the quantitative relationships between varying doses of a stressor and multiple distinct biological responses simultaneously, distinguishing itself from single-endpoint approaches by integrating correlated outcomes to improve inference accuracy and capture complex, system-level hormetic effects.

5

Publications

200

Citations

37

Authors

23

Institutions

Publications per year

2017–2026

1

Parents

Publications

5

Multiple Co-primary Endpoints: Medical and Statistical Solutions: A Report from the Multiple Endpoints Expert Team of the Pharmaceutical Research and Manufacturers of America

Walter Offen, Christy Chuang‐Stein, Alex Dmitrienko et al. · Drug Information Journal · 2007 · 125 citations · Full text

, , +14

Hormesis - Implications for risk assessment caloric intake (body weight) as an exemplar

Angelo Turturro, Bruce S. Hass, Ronald W. Hart · Human & Experimental Toxicology · 1998 · 21 citations

, , +17

A proposal for a novel rationale for critical effect size in dose–response analysis based on a multi-endpoint<i>in vivo</i>study with methyl methanesulfonate

Andreas Zeller, Leilei Tang, Stephen D. Dertinger et al. · Mutagenesis · 2015 · 20 citations · Full text

, , +16

Study on the characterization of pesticide modes of action similarity and the multi-endpoint combined toxicity of pesticide mixtures to Caenorhabditis elegans

Peng Huang, Shu‐Shen Liu, Zejun Wang et al. · The Science of The Total Environment · 2023 · 19 citations

, , +17

Partition testing in dose–response studies with multiple endpoints

Yi Liu, Jason C. Hsu, Stephen J. Ruberg · Pharmaceutical Statistics · 2007 · 15 citations

, , +12

1–5 of 5

Authors

37

  1. DH
    David Henry

    University of Newcastle Australia, Australia

    1 publications · 125 citations

    1

    h-index

  2. CY
    C Yeh

    Procter & Gamble (United States), United States

    1 publications · 125 citations

    1

    h-index

  3. KC
    Kun Chen

    University of Connecticut, United States

    1 publications · 125 citations

    1

    h-index

  4. BS
    Bruce S. Hass

    National Center for Toxicological Research, United States

    1 publications · 21 citations

    1

    h-index

  5. ZG
    Zhong-Wei Gu

    Tongji University, China

    1 publications · 19 citations

    1

    h-index

1–5 of 37

Institutions

23

  1. Eli Lilly (United States)

    Indianapolis, United States

    2 h-index

    3 publications

    265 citations

  2. Biogen (United States)

    Cambridge, United States

    1 h-index

    1 publications

    125 citations

  3. Roche (Switzerland)

    Basel, Switzerland

    1 h-index

    5 publications

    100 citations

  4. Tongji University

    Shanghai, China

    1 h-index

    5 publications

    95 citations

  5. Suzhou University of Science and Technology

    Suzhou, China

    1 h-index

    1 publications

    19 citations

  6. Qiagen (Switzerland)

    Hombrechtikon, Switzerland

    1 h-index

    1 publications

    20 citations

  7. The Ohio State University

    Columbus, United States

    1 h-index

    2 publications

    30 citations

  8. Bayer (United States)

    Whippany, United States

    1 h-index

    1 publications

    125 citations

1–8 of 23

Venues

  1. Human & Experimental Toxicology

    1 publications · 21 citations

    1

    h-index

  2. The Science of The Total Environment

    1 publications · 19 citations

    1

    h-index

  3. Pharmaceutical Statistics

    1 publications · 15 citations

    1

    h-index

  4. Mutagenesis

    1 publications · 20 citations

    1

    h-index

  5. Drug Information Journal

    DIA · 1 publications · 125 citations

    1

    h-index

1–5