Concepedia

Morphogen Source-sink Dynamics

Morphogen Source-Sink Dynamics is a theoretical framework in developmental biology that describes the establishment and maintenance of morphogen gradients through the localized production of signaling molecules at a source and their directed depletion or degradation at a sink, thereby governing spatial patterning in embryonic tissues.

29

Publications

2.7K

Citations

102

Authors

66

Institutions

Publications per year

2017–2026

4

Parents

Publications

29

Stability and Nuclear Dynamics of the Bicoid Morphogen Gradient

Thomas Gregor, Eric Wieschaus, Alistair P. McGregor et al. · Cell · 2007 · 538 citations · Full text

, , +14

Do Morphogen Gradients Arise by Diffusion?

Arthur D. Lander, Qing Nie, Frederic Y. M. Wan · Developmental Cell · 2002 · 417 citations · Full text

, , +12

An abiotic model for stromatolite morphogenesis

J. P. Grotzinger, Daniel H. Rothman · Nature · 1996 · 396 citations

, , +9

Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules

Shuizi Rachel Yu, Markus Burkhardt, Matthias Nowak et al. · Nature · 2009 · 390 citations

, , +14

The development of eyespot patterns on butterfly wings: morphogen sources or sinks?

Vernon French, Paul M. Brakefield · Development · 1992 · 115 citations · Full text

, , +16

1–5 of 29

Authors

102

  1. FY
    Frederic Y. M. Wan

    University of California, Irvine, United States

    2 publications · 427 citations

    2

    h-index

  2. AD
    Arthur D. Lander

    University of California, Irvine, United States

    2 publications · 427 citations

    2

    h-index

  3. QN
    Qing Nie

    University of California, Irvine, United States

    2 publications · 427 citations

    2

    h-index

  4. JS
    Juan Soler

    Universidad de Granada, Spain

    2 publications · 60 citations

    2

    h-index

  5. JM
    José M. Mazón

    Universitat de València, Spain

    2 publications · 60 citations

    2

    h-index

1–5 of 102

Institutions

66

  1. Universitat de València

    Valencia, Spain

    2 h-index

    3 publications

    85 citations

  2. Universidad de Granada

    Granada, Spain

    2 h-index

    5 publications

    155 citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    3 publications

    1.2K citations

  4. University of Edinburgh

    Edinburgh, United Kingdom

    2 h-index

    3 publications

    325 citations

  5. Princeton University

    Princeton, United States

    2 h-index

    11 publications

    3.2K citations

  6. University of California, Irvine

    Irvine, United States

    2 h-index

    7 publications

    1.3K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    5 publications

    195 citations

  8. Agency for Science, Technology and Research

    Singapore, Singapore

    1 h-index

    1 publications

    17 citations

1–8 of 66

Venues

  1. Nature

    2 publications · 786 citations

    2

    h-index

  2. Bulletin of Mathematical Biology

    2 publications · 46 citations

    2

    h-index

  3. Developmental Cell

    2 publications · 503 citations

    2

    h-index

  4. eLife

    2 publications · 122 citations

    2

    h-index

  5. Development

    1 publications · 115 citations

    1

    h-index

1–5