Molecular Replacement is a phase solution method in X-ray crystallography that determines the three-dimensional structure of a macromolecule by using a known homologous structure as an initial model to estimate the missing phase information from diffraction data.
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<i>Phaser</i>crystallographic software
Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al. · Journal of Applied Crystallography · 2007 · 20.9K citations · Full text
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