Concepedia

Molecular Chaperone Engineering

Molecular Chaperone Engineering is a genetic engineering framework that specifically modifies or designs molecular chaperones to enhance protein folding stability and cellular stress resilience under adverse conditions.

84

Publications

4.1K

Citations

459

Authors

172

Institutions

Publications per year

2017–2026

23

Parents

Publications

84

Chaperonin overexpression promotes genetic variation and enzyme evolution

Nobuhiko Tokuriki, Dan S. Tawfik · Nature · 2009 · 369 citations

, , +16

Chaperone-based procedure to increase yields of soluble recombinant proteins produced in E. coli

Ario de Marco, Elke Deuerling, Axel Mogk et al. · BMC Biotechnology · 2007 · 286 citations · Full text

, , +17

Genetic selection designed to stabilize proteins uncovers a chaperone called Spy

Shu Quan, Philipp Koldewey, Tim L. Tapley et al. · Nature Structural & Molecular Biology · 2011 · 178 citations · Full text

, , +9

Native folding of aggregation-prone recombinant proteins in Escherichia coli by osmolytes, plasmid- or benzyl alcohol–overexpressed molecular chaperones

Ario de Marco, Sophia Diamant, Pierre Goloubinoff · Cell Stress and Chaperones · 2005 · 166 citations · Full text

, , +17

Protocol for preparing proteins with improved solubility by co-expressing with molecular chaperones in Escherichia coli

Ario de Marco · Nature Protocols · 2007 · 123 citations

, , +16

1–5 of 84

Authors

459

  1. TA
    Takuzo Aida

    The University of Tokyo, Japan

    4 publications · 180 citations

    4

    h-index

  2. AD
    Ario de Marco

    University of Nova Gorica, Slovenia

    3 publications · 575 citations

    3

    h-index

  3. KA
    Kazunari Akiyoshi

    Kyoto University, Japan

    3 publications · 85 citations

    3

    h-index

  4. SS
    Seunghyun Sim

    The University of Tokyo, Japan

    3 publications · 86 citations

    3

    h-index

  5. HT
    Hideki Taguchi

    Tokyo Institute of Technology, Japan

    3 publications · 143 citations

    3

    h-index

1–5 of 459

Institutions

172

  1. The University of Tokyo

    Tokyo, Japan

    6 h-index

    18 publications

    939 citations

  2. Kyoto University

    Kyoto, Japan

    5 h-index

    15 publications

    434 citations

  3. The University of Osaka

    Osaka, Japan

    3 h-index

    11 publications

    396 citations

  4. RIKEN Center for Emergent Matter Science

    Wako, Japan

    3 h-index

    5 publications

    120 citations

  5. Tsinghua University

    Beijing, China

    3 h-index

    15 publications

    453 citations

  6. Heidelberg University

    Heidelberg, Germany

    2 h-index

    4 publications

    868 citations

  7. Tokyo Institute of Technology

    Tokyo, Japan

    2 h-index

    4 publications

    98 citations

  8. Gunma University

    Maebashi, Japan

    2 h-index

    2 publications

    194 citations

1–8 of 172

Venues

  1. Journal of Biotechnology

    6 publications · 142 citations

    6

    h-index

  2. Journal of the American Chemical Society

    JACS · 4 publications · 200 citations

    4

    h-index

  3. Protein Science

    PS · 3 publications · 86 citations

    3

    h-index

  4. Biotechnology and Bioengineering

    3 publications · 156 citations

    3

    h-index

  5. Applied Microbiology and Biotechnology

    3 publications · 69 citations

    3

    h-index

1–5