Model-based Dose-proportionality Testing

Model-Based Dose-Proportionality Testing is a statistical methodology within pharmacokinetic analysis that uses formal mathematical models to characterize the relationship between dose and systemic exposure, distinguishing itself by explicitly modeling dose-proportionality as a function of dose levels through parametric estimation and hypothesis testing.

Publications

618

Citations

Authors

Institutions

Publications per year

2017–2026

Parents

Dose-proportionality Analysis

Publications

Confidence Interval Criteria for Assessment of Dose Proportionality

Brian P. Smith · Pharmaceutical Research · 2000 · 352 citations

Pharmacy, Biostatistics, Dose-response Modeling +13

Assessment of Dose Proportionality: Report from the Statisticians in the Pharmaceutical Industry/Pharmacokinetics UK Joint Working Party

Kevin Gough, Michael G. Hutchison, Oliver N. Keene et al. · Drug Information Journal · 1995 · 266 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

1–2 of 2

Authors

JM
John McKellar
VA Palo Alto Health Care System, United States
1 publications · 266 citations
1
h-index
KG
Kevin Gough
St. Michael's Hospital, Canada
1 publications · 266 citations
1
h-index
SE
Stuart Ellis
Napp Pharmaceuticals (United Kingdom), United Kingdom
1 publications · 266 citations
1
h-index
BB
Bill Byrom
Critical Path Institute, United States
1 publications · 266 citations
1
h-index
BP
Brian P. Smith
University of Pennsylvania, United States
1 publications · 352 citations
1
h-index

1–5 of 8

Institutions

1–7 of 7

Venues

Pharmaceutical Research
1 publications · 352 citations
1
h-index
Drug Information Journal
DIA · 1 publications · 266 citations
1
h-index

1–2