Concepedia

Minichromosome Construction

Minichromosome Construction is a methodological framework in chromosome engineering that enables the assembly of functional, structurally minimized chromosomes through the strategic integration of essential chromosomal elements, thereby distinguishing it from conventional chromosome manipulation techniques by its focus on de novo synthesis and autonomous replication capacity.

66

Publications

3.5K

Citations

283

Authors

105

Institutions

Publications per year

2017–2026

8

Parents

Publications

66

Targeting of a tetracycline-inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei

Bill Wickstead, Klaus Ersfeld, Keith Gull · Molecular and Biochemical Parasitology · 2002 · 267 citations

, , +11

Neocentromere activity of structurally acentric mini-chromosomes in Drosophila

Byron C. Williams, Terence D. Murphy, Michael L. Goldberg et al. · Nature Genetics · 1998 · 191 citations

, , +14

Construction and behavior of engineered minichromosomes in maize

Weichang Yu, Fangpu Han, Zhi Gao et al. · Proceedings of the National Academy of Sciences · 2007 · 160 citations · Full text

, , +17

Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts

Yoshimi Kuroiwa, Kazuma Tomizuka, Tokuyuki Shinohara et al. · Nature Biotechnology · 2000 · 154 citations

, , +9

Generation of a human X‐derived minichromosome using telomere‐associated chromosome fragmentation.

Christine J. Farr, Rosemary A. L. Bayne, David Kipling et al. · The EMBO Journal · 1995 · 126 citations

, , +13

1–5 of 66

Authors

283

  1. BW
    Bill Wickstead

    University of Oxford, United Kingdom

    3 publications · 414 citations

    3

    h-index

  2. FA
    Fiorentina Ascenzioni

    Sapienza University of Rome, Italy

    3 publications · 97 citations

    3

    h-index

  3. PD
    Pierluigi Donini

    Sapienza University of Rome, Italy

    3 publications · 97 citations

    3

    h-index

  4. MY
    Mitsuhiro Yanagida

    Kyoto University, Japan

    3 publications · 225 citations

    3

    h-index

  5. JA
    James A. Birchler

    University of Missouri, United States

    3 publications · 232 citations

    3

    h-index

1–5 of 283

Institutions

105

  1. University of Edinburgh

    Edinburgh, United Kingdom

    5 h-index

    10 publications

    361 citations

  2. University of Missouri

    Columbia, United States

    3 h-index

    16 publications

    1.2K citations

  3. Istituto Pasteur

    Rome, Italy

    3 h-index

    10 publications

    296 citations

  4. Murdoch Children's Research Institute

    Melbourne, Australia

    3 h-index

    14 publications

    852 citations

  5. Royal Children's Hospital

    Melbourne, Australia

    3 h-index

    14 publications

    852 citations

  6. Kyoto University

    Kyoto, Japan

    3 h-index

    13 publications

    943 citations

  7. Cornell University

    Ithaca, United States

    3 h-index

    7 publications

    535 citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    5 publications

    392 citations

1–8 of 105

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 597 citations

    7

    h-index

  2. Molecular and Cellular Biology

    MCB · 4 publications · 158 citations

    4

    h-index

  3. Nature Genetics

    2 publications · 272 citations

    2

    h-index

  4. Journal of Molecular Biology

    JMB · 2 publications · 83 citations

    2

    h-index

  5. Humana Press eBooks

    Ebook platform · 2 publications · 96 citations

    2

    h-index

1–5