Concepedia

Microtubule Instability

Microtubule Instability is a dynamic behavioral property of microtubules characterized by stochastic switching between phases of polymerization and depolymerization, driven by GTP hydrolysis in tubulin subunits, which enables rapid reorganization of the cytoskeleton in response to cellular signals.

587

Publications

58.1K

Citations

2.1K

Authors

652

Institutions

Publications per year

2017–2026

98

Variants

Dynamic Instability

Parents

Publications

587

Dynamic instability of microtubule growth

Tim Mitchison, Marc W. Kirschner · Nature · 1984 · 3.4K citations

, , +12

Taxol stabilizes microtubules in mouse fibroblast cells.

Peter B. Schiff, S. B. Horwitz · Proceedings of the National Academy of Sciences · 1980 · 2K citations · Full text

, , +17

Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies.

R. A. Walker, E. Timothy O’Brien, Nancy Pryer et al. · The Journal of Cell Biology · 1988 · 1K citations · Full text

, , +17

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.

David Drechsel, Anthony A. Hyman, Melanie H. Cobb et al. · Molecular Biology of the Cell · 1992 · 973 citations

, , +17

Microtubules containing acetylated alpha-tubulin in mammalian cells in culture.

G Piperno, Michel Ledizet, Xiaotian Chang · The Journal of Cell Biology · 1987 · 854 citations · Full text

, , +16

1–5 of 587

Authors

2.1K

  1. LW
    Leslie Wilson

    University of California, Santa Barbara, United States

    31 publications · 3.2K citations

    29

    h-index

  2. MA
    Mary Ann Jordan

    University of California, Santa Barbara, United States

    26 publications · 4K citations

    26

    h-index

  3. LC
    Lynne Cassimeris

    Lehigh University, United States

    22 publications · 2.2K citations

    18

    h-index

  4. ED
    Edward D. Salmon

    University of North Carolina at Chapel Hill, United States

    14 publications · 1.9K citations

    14

    h-index

  5. DP
    Dulal Panda

    Indian Institute of Technology Bombay, India

    12 publications · 1K citations

    12

    h-index

1–5 of 2.1K

Institutions

652

  1. University of California, Santa Barbara

    Santa Barbara, United States

    35 h-index

    172 publications

    21.4K citations

  2. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    22 h-index

    74 publications

    14.9K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    21 h-index

    105 publications

    11K citations

  4. Inserm

    Paris, France

    18 h-index

    66 publications

    6.8K citations

  5. Lehigh University

    Bethlehem, United States

    16 h-index

    50 publications

    4.9K citations

  6. University of California, San Francisco

    San Francisco, United States

    14 h-index

    34 publications

    15.2K citations

  7. Vanderbilt University

    Nashville, United States

    14 h-index

    47 publications

    2.4K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    13 h-index

    30 publications

    2.8K citations

1–8 of 652

Venues

  1. The Journal of Cell Biology

    JCB · 49 publications · 9.2K citations

    44

    h-index

  2. Molecular Biology of the Cell

    MBC · 38 publications · 5.3K citations

    32

    h-index

  3. Journal of Biological Chemistry

    JBC · 38 publications · 3K citations

    30

    h-index

  4. Journal of Cell Science

    30 publications · 2.3K citations

    23

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 24 publications · 4.6K citations

    23

    h-index

1–5