Concepedia

Microrna-responsive Expression

MicroRNA-Responsive Expression is a transgene expression control mechanism that selectively modulates gene expression in response to specific microRNAs by incorporating microRNA-binding sites into the transgene's regulatory regions, thereby enabling post-transcriptional regulation contingent on the endogenous microRNA expression profile.

122

Publications

20K

Citations

729

Authors

277

Institutions

Publications per year

2017–2026

34

Variants

Mirna-responsive Expression

Parents

Publications

122

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Lee P. Lim, Nelson C. Lau, Philip W. Garrett-Engele et al. · Nature · 2005 · 4.8K citations

, , +16

Adipose-derived circulating miRNAs regulate gene expression in other tissues

Thomas Thomou, Marcelo A. Mori, Jonathan M. Dreyfuss et al. · Nature · 2017 · 1.6K citations · Full text

, , +14

MicroRNA-373 induces expression of genes with complementary promoter sequences

Robert F. Place, Long‐Cheng Li, Deepa Pookot et al. · Proceedings of the National Academy of Sciences · 2008 · 1.2K citations · Full text

, , +13

Gene Regulation by Transcription Factors and MicroRNAs

Oliver Hobert · Science · 2008 · 937 citations

, , +12

MicroRNAs in the Human Heart

Thomas Thum, Paolo Galuppo, Christian Wolf et al. · Circulation · 2007 · 886 citations · Full text

, , +17

1–5 of 122

Authors

729

  1. SG
    Steven Grinspoon

    Massachusetts General Hospital, United States

    2 publications · 1.6K citations

    2

    h-index

  2. TT
    Thomas Thomou

    Harvard University, United States

    2 publications · 1.6K citations

    2

    h-index

  3. CW
    Christian Wolfrum

    ETH Zurich, Switzerland

    2 publications · 1.6K citations

    2

    h-index

  4. JM
    Jonathan M. Dreyfuss

    Harvard University, United States

    2 publications · 1.6K citations

    2

    h-index

  5. RG
    Rubén García-Martín

    Joslin Diabetes Center, United States

    2 publications · 1.6K citations

    2

    h-index

1–5 of 729

Institutions

277

  1. Harvard University

    Cambridge, United States

    7 h-index

    49 publications

    25.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    9 publications

    3.6K citations

  3. Massachusetts General Hospital

    Boston, United States

    4 h-index

    22 publications

    7K citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    4 h-index

    13 publications

    17.7K citations

  5. Center for Cancer Research

    Bethesda, United States

    3 h-index

    15 publications

    4.7K citations

  6. Nanjing Agricultural University

    Nanjing, China

    3 h-index

    17 publications

    672 citations

  7. Yale University

    New Haven, United States

    3 h-index

    7 publications

    1.5K citations

  8. Boston Children's Hospital

    Boston, United States

    3 h-index

    9 publications

    2.8K citations

1–8 of 277

Venues

  1. Journal of Biological Chemistry

    JBC · 4 publications · 1.2K citations

    4

    h-index

  2. Nature

    3 publications · 6.9K citations

    3

    h-index

  3. Genes & Development

    2 publications · 236 citations

    2

    h-index

  4. PubMed

    Repository · 2 publications · 73 citations

    2

    h-index

  5. Nucleic Acids Research

    2 publications · 29 citations

    2

    h-index

1–5