Concepedia

Microinjection

Microinjection is a physical delivery method that involves the direct introduction of genome editing components into a target cell through a fine glass needle guided by microscopic visualization, distinguished from other delivery techniques by its precision at the single-cell level and reliance on mechanical penetration of the cell membrane.

1.6K

Publications

99.4K

Citations

6.4K

Authors

1.5K

Institutions

Publications per year

2017–2026

207

Parents

Publications

1.6K

High-velocity microprojectiles for delivering nucleic acids into living cells

Theodore M. Klein, E. D. Wolf, Rong‐Ching Wu et al. · Nature · 1987 · 1.4K citations

, , +16

Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase

Mutsuki Amano, Kazuyasu Chihara, Kazushi Kimura et al. · Science · 1997 · 1.1K citations

, , +17

High efficiency transformation by direct microinjection of DNA into cultured mammalian cells

Mario R. Capecchi · Cell · 1980 · 1K citations

, , +10

The Ras-Related Protein Cdc42Hs and Bradykinin Promote Formation of Peripheral Actin Microspikes and Filopodia in Swiss 3T3 Fibroblasts

Robert Kozma, Sohail Ahmed, Anthony Best et al. · Molecular and Cellular Biology · 1995 · 1K citations · Full text

, , +15

Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

Aron M. Geurts, Gregory J. Cost, Yevgeniy Freyvert et al. · Science · 2009 · 919 citations · Full text

, , +8

1–5 of 1.6K

Authors

6.4K

  1. DS
    Dong Sun

    City University of Hong Kong, Hong Kong SAR China

    13 publications · 909 citations

    12

    h-index

  2. SH
    Shuk Han Cheng

    City University of Hong Kong, Hong Kong SAR China

    10 publications · 836 citations

    10

    h-index

  3. MR
    Martin Rechsteiner

    University of Utah, United States

    9 publications · 559 citations

    9

    h-index

  4. YS
    Yu Sun

    University of Toronto, Canada

    8 publications · 736 citations

    8

    h-index

  5. RA
    Robson A.S. Santos

    Universidade Federal de Minas Gerais, Brazil

    8 publications · 333 citations

    8

    h-index

1–5 of 6.4K

Institutions

1.5K

  1. Centre National de la Recherche Scientifique

    Paris, France

    25 h-index

    97 publications

    7.3K citations

  2. Inserm

    Paris, France

    21 h-index

    111 publications

    11.5K citations

  3. Harvard University

    Cambridge, United States

    18 h-index

    55 publications

    5.6K citations

  4. Universidade de São Paulo

    São Paulo, Brazil

    16 h-index

    65 publications

    1.8K citations

  5. University of Toronto

    Toronto, Canada

    15 h-index

    54 publications

    5.5K citations

  6. Johns Hopkins University

    Baltimore, United States

    14 h-index

    38 publications

    2.8K citations

  7. National Institutes of Health

    Bethesda, United States

    14 h-index

    54 publications

    5K citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    14 h-index

    36 publications

    2.2K citations

1–8 of 1.5K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 51 publications · 5.7K citations

    38

    h-index

  2. Journal of Neuroscience

    29 publications · 5K citations

    29

    h-index

  3. The Journal of Cell Biology

    JCB · 29 publications · 3.7K citations

    28

    h-index

  4. 26

    h-index

  5. Brain Research

    34 publications · 2.1K citations

    23

    h-index

1–5