Concepedia

Microbiota-induced Tolerance

Microbiota-Induced Tolerance is a biological mechanism within the broader category of mucosal tolerance whereby persistent exposure to commensal microbiota in the gastrointestinal tract drives the differentiation of regulatory immune cells that specifically suppress inflammatory responses against benign microbial antigens.

52

Publications

10.1K

Citations

385

Authors

158

Institutions

Publications per year

2017–2026

15

Parents

Publications

52

The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction

Nobuyuki Sudo, S. Sawamura, Kazuo Tanaka et al. · The Journal of Immunology · 1997 · 1.1K citations · Full text

, , +17

Peripheral education of the immune system by colonic commensal microbiota

Stephanie K. Lathrop, Seth M. Bloom, Sindhuja Rao et al. · Nature · 2011 · 1K citations

, , +17

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

Rainer Duchmann, I Kaiser, E Hermann et al. · Clinical & Experimental Immunology · 1995 · 949 citations · Full text

, , +17

Individual intestinal symbionts induce a distinct population of RORγ <sup>+</sup> regulatory T cells

Esen Sefik, Naama Geva‐Zatorsky, Sungwhan F. Oh et al. · Science · 2015 · 879 citations · Full text

, , +17

The microbiota regulates type 2 immunity through RORγt <sup>+</sup> T cells

Caspar Ohnmacht, Joo-Hong Park, Sascha Cording et al. · Science · 2015 · 869 citations

, , +17

1–5 of 52

Authors

385

  1. KT
    Kazuo Tanaka

    University of Electro-Communications, Japan

    2 publications · 1.2K citations

    2

    h-index

  2. MC
    Matthew C. Walsh

    University of Pennsylvania, United States

    2 publications · 92 citations

    2

    h-index

  3. YC
    Yongwon Choi

    University of Pennsylvania, United States

    2 publications · 92 citations

    2

    h-index

  4. YA
    Y. Aiba

    Tokai University, Japan

    2 publications · 1.2K citations

    2

    h-index

  5. CO
    Caspar Ohnmacht

    Helmholtz Zentrum München, Germany

    2 publications · 897 citations

    2

    h-index

1–5 of 385

Institutions

158

  1. Harvard University

    Cambridge, United States

    3 h-index

    15 publications

    8.8K citations

  2. Helmholtz Zentrum München

    Munich, Germany

    2 h-index

    2 publications

    897 citations

  3. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    17 publications

    1.2K citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    9 publications

    660 citations

  5. Brigham and Women's Hospital

    Boston, United States

    2 h-index

    7 publications

    4K citations

  6. The University of Tokyo

    Tokyo, Japan

    2 h-index

    4 publications

    1.9K citations

  7. University of Minnesota

    Minneapolis, United States

    2 h-index

    3 publications

    955 citations

  8. Pohang University of Science and Technology

    Pohang, South Korea

    2 h-index

    7 publications

    147 citations

1–8 of 158

Venues

  1. Science

    5 publications · 3.1K citations

    5

    h-index

  2. The Journal of Immunology

    JI · 2 publications · 1.2K citations

    2

    h-index

  3. Hepatology Research

    2 publications · 98 citations

    2

    h-index

  4. Immunity

    2 publications · 239 citations

    2

    h-index

  5. Clinical & Experimental Immunology

    CEI · 2 publications · 1.1K citations

    2

    h-index

1–5