Concepedia

Mhc Peptide Loading

MHC Peptide Loading is a molecular immunology process that refers to the selective association of antigenic peptides with major histocompatibility complex molecules in the endoplasmic reticulum, a critical step enabling CD8+ or CD4+ T cell recognition of infected or malignant cells.

358

Publications

27.9K

Citations

1.6K

Authors

443

Institutions

Publications per year

2017–2026

47

Parents

Publications

358

Activation of Lysosomal Function During Dendritic Cell Maturation

E. Sergio Trombetta, Melanie Ebersold, Wendy S. Garrett et al. · Science · 2003 · 728 citations

, , +17

Roles for Calreticulin and a Novel Glycoprotein, Tapasin, in the Interaction of MHC Class I Molecules with TAP

Bhanu Sadasivan, Bodo Ortmann, Thomas A. Spies et al. · Immunity · 1996 · 695 citations · Full text

, , +17

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

Lisa Denzin, Peter Cresswell · Cell · 1995 · 681 citations · Full text

, , +14

Essential Role for Cathepsin S in MHC Class II–Associated Invariant Chain Processing and Peptide Loading

Richard J. Riese, Paula Wolf, Dieter Brömme et al. · Immunity · 1996 · 529 citations · Full text

, , +16

Cathepsin S Required for Normal MHC Class II Peptide Loading and Germinal Center Development

Guo‐Ping Shi, Jóse A. Villadangos, Glenn Dranoff et al. · Immunity · 1999 · 522 citations · Full text

, , +14

1–5 of 358

Authors

1.6K

  1. RT
    Robert Tampé

    Goethe University Frankfurt, Germany

    25 publications · 2K citations

    23

    h-index

  2. PC
    Peter Cresswell

    Yale University, United States

    19 publications · 2.7K citations

    19

    h-index

  3. JN
    Jacques Neefjes

    The Netherlands Cancer Institute, Netherlands

    17 publications · 1.3K citations

    17

    h-index

  4. SS
    Sebastian Springer

    Constructor University, Germany

    10 publications · 498 citations

    10

    h-index

  5. FM
    Frank Momburg

    German Cancer Research Center, Germany

    10 publications · 778 citations

    10

    h-index

1–5 of 1.6K

Institutions

443

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    27 h-index

    101 publications

    15.7K citations

  2. Yale University

    New Haven, United States

    26 h-index

    74 publications

    15.9K citations

  3. Goethe University Frankfurt

    Frankfurt am Main, Germany

    22 h-index

    87 publications

    6.6K citations

  4. Heidelberg University

    Heidelberg, Germany

    20 h-index

    68 publications

    5.7K citations

  5. Inserm

    Paris, France

    18 h-index

    95 publications

    8.8K citations

  6. German Cancer Research Center

    Heidelberg, Germany

    17 h-index

    54 publications

    4.3K citations

  7. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    16 h-index

    55 publications

    7K citations

  8. University of Tübingen

    Tübingen, Germany

    15 h-index

    47 publications

    2.1K citations

1–8 of 443

Venues

  1. The Journal of Immunology

    JI · 85 publications · 4.4K citations

    42

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 30 publications · 3.6K citations

    26

    h-index

  3. European Journal of Immunology

    EJI · 28 publications · 1.9K citations

    24

    h-index

  4. Journal of Biological Chemistry

    JBC · 19 publications · 848 citations

    17

    h-index

  5. Immunity

    13 publications · 3.8K citations

    13

    h-index

1–5