Concepedia

Methylphenidate Toxicity

Methylphenidate Toxicity is a clinical condition characterized by adverse physiological and neurological effects resulting from the excessive intake or impaired metabolism of methylphenidate, a central nervous system stimulant, distinguished from other stimulant toxicities by its specific pharmacological action on dopamine and norepinephrine reuptake inhibition.

162

Publications

6.5K

Citations

610

Authors

258

Institutions

Publications per year

2017–2026

7

Parents

Publications

162

A 90-day oral gavage toxicity study of d-methylphenidate and d,l-methylphenidate in Sprague–Dawley rats

Steve Teo, David Stirling, Steve D. Thomas et al. · Toxicology · 2002 · 347 citations

, , +10

Phase III, Randomized, Double-Blind, Placebo-Controlled Study of Long-Acting Methylphenidate for Cancer-Related Fatigue: North Central Cancer Treatment Group NCCTG-N05C7 Trial

Amanda R. Moraska, Amit Sood, Shaker R. Dakhil et al. · Journal of Clinical Oncology · 2010 · 172 citations · Full text

, , +17

Clinical Studies of Methylphenidate Serum Levels in Children and Adults

C. Thomas Gualtieri, William A. Wargin, Robert C. Kanoy et al. · Journal of the American Academy of Child Psychiatry · 1982 · 142 citations

, , +7

Amphetamine induces depletion of dopamine and loss of dopamine uptake sites in caudate

Caroline Wagner, G.A. Ricaurte, Chris E. Johanson et al. · Neurology · 1980 · 137 citations

, , +17

Intravenous methylphenidate abuse. Prototype for prescription drug abuse.

Theodore V. Parran, Donald R. Jasinski · PubMed · 1991 · 136 citations

, , +16

1–5 of 162

Authors

610

  1. DR
    Daniel R. Doerge

    National Center for Toxicological Research, United States

    5 publications · 166 citations

    5

    h-index

  2. SD
    Steve D. Thomas

    Bristol-Myers Squibb (Switzerland), Switzerland

    5 publications · 472 citations

    5

    h-index

  3. VK
    Vikram Khetani

    Bristol-Myers Squibb (Switzerland), Switzerland

    5 publications · 472 citations

    5

    h-index

  4. DS
    David Stirling

    Bristol-Myers Squibb (Switzerland), Switzerland

    5 publications · 472 citations

    5

    h-index

  5. SK
    Steve K. Teo

    Bristol-Myers Squibb (Switzerland), Switzerland

    4 publications · 125 citations

    4

    h-index

1–5 of 610

Institutions

258

  1. National Center for Toxicological Research

    Pine Bluff, United States

    5 h-index

    46 publications

    1.5K citations

  2. United States Food and Drug Administration

    Silver Spring, United States

    5 h-index

    41 publications

    1.3K citations

  3. Novartis (Switzerland)

    Basel, Switzerland

    4 h-index

    6 publications

    147 citations

  4. Novartis (United States)

    New York, United States

    4 h-index

    9 publications

    153 citations

  5. Universidade do Extremo Sul Catarinense

    Criciúma, Brazil

    4 h-index

    24 publications

    1.2K citations

  6. Iran University of Medical Sciences

    Tehran, Iran

    3 h-index

    6 publications

    264 citations

  7. University of Pittsburgh

    Pittsburgh, United States

    3 h-index

    9 publications

    777 citations

  8. Eunice Kennedy Shriver National Institute of Child Health and Human Development

    Bethesda, United States

    3 h-index

    3 publications

    94 citations

1–8 of 258

Venues

  1. PubMed

    Repository · 11 publications · 430 citations

    10

    h-index

  2. JAMA

    9 publications · 475 citations

    9

    h-index

  3. Journal of Child and Adolescent Psychopharmacology

    JCAP · 8 publications · 445 citations

    8

    h-index

  4. 5

    h-index

  5. Archives of Internal Medicine

    5 publications · 256 citations

    5

    h-index

1–5