Concepedia

Methylation-dependent Interactions

Methylation-Dependent Interactions is a molecular recognition mechanism in which protein-protein or protein-nucleic acid interactions are specifically mediated by the presence of methylated amino acid residues, thereby enabling selective binding events that regulate chromatin dynamics, gene expression, or signal transduction in a methylation-dependent manner.

263

Publications

22.8K

Citations

1.3K

Authors

443

Institutions

Publications per year

2017–2026

45

Parents

Publications

263

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

Joan Boyes, Adrian Bird · Cell · 1991 · 729 citations

, , +12

Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase

Bas van Steensel, Steven Henikoff · Nature Biotechnology · 2000 · 646 citations

, , +16

Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation

Marilyn G. Pray-Grant, J. Daniel, David Schieltz et al. · Nature · 2005 · 509 citations

, , +14

Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics

Gi-Bang Koo, Da‐Gyum Lee, Woo-Jung Kim et al. · Cell Research · 2015 · 500 citations · Full text

, , +16

Tudor, MBT and chromo domains gauge the degree of lysine methylation

Jeesun Kim, J. Daniel, Alexsandra Espejo et al. · EMBO Reports · 2006 · 485 citations · Full text

, , +10

1–5 of 263

Authors

1.3K

  1. AJ
    Albert Jeltsch

    University of Stuttgart, Germany

    6 publications · 365 citations

    6

    h-index

  2. XC
    Xiaodong Cheng

    Emory University, United States

    6 publications · 887 citations

    6

    h-index

  3. MT
    Mark T. Bedford

    The University of Texas MD Anderson Cancer Center, United States

    6 publications · 712 citations

    6

    h-index

  4. JH
    J.R. Horton

    Emory University, United States

    5 publications · 761 citations

    5

    h-index

  5. AB
    Adrian Bird

    University of Edinburgh, United Kingdom

    4 publications · 824 citations

    4

    h-index

1–5 of 1.3K

Institutions

443

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    11 h-index

    24 publications

    2.2K citations

  2. Harvard University

    Cambridge, United States

    10 h-index

    28 publications

    2.3K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    25 publications

    6.2K citations

  4. Inserm

    Paris, France

    7 h-index

    27 publications

    1.7K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    27 publications

    3K citations

  6. Emory University

    Atlanta, United States

    6 h-index

    26 publications

    4K citations

  7. The University of Tokyo

    Tokyo, Japan

    6 h-index

    21 publications

    1.9K citations

  8. National Institutes of Health

    Bethesda, United States

    6 h-index

    21 publications

    1.3K citations

1–8 of 443

Venues

  1. Journal of Biological Chemistry

    JBC · 27 publications · 2K citations

    23

    h-index

  2. Nucleic Acids Research

    22 publications · 1.1K citations

    16

    h-index

  3. Biochemistry

    11 publications · 488 citations

    11

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 1.1K citations

    9

    h-index

  5. Molecular Cell

    7 publications · 1.3K citations

    7

    h-index

1–5