Concepedia

Methadone Rotation

Methadone Rotation is a clinical pharmacological strategy within opioid rotation that involves the substitution of a patient’s current opioid regimen with methadone, distinguished by its unique pharmacokinetic and pharmacodynamic properties, including long half-life, potent mu-opioid receptor agonism, and N-methyl-D-aspartate (NMDA) receptor antagonism, to optimize analgesia while minimizing adverse effects or opioid-induced hyperalgesia.

25

Publications

1.6K

Citations

89

Authors

38

Institutions

Publications per year

2017–2026

1

Parents

Publications

25

Establishing “Best Practices” for Opioid Rotation: Conclusions of an Expert Panel

Perry G. Fine, Russell K. Portenoy · Journal of Pain and Symptom Management · 2009 · 265 citations · Full text

, , +15

Dose ratio between morphine and methadone in patients with cancer pain: a retrospective study.

Peadar G. Lawlor, Kyle Turner, John Hanson et al. · PubMed · 1998 · 171 citations

, , +17

Dose ratio between morphine and methadone in patients with cancer pain

Peter G. Lawlor, Ken S. Turner, John Hanson et al. · Cancer · 1998 · 152 citations · Full text

, , +17

Switching from Methadone to a Different Opioid: What Is the Equianalgesic Dose Ratio?

Paul W. Walker, Shana L. Palla, Be-Lian Pei et al. · Journal of Palliative Medicine · 2008 · 101 citations · Full text

, , +17

Methadone initiation and rotation in the outpatient setting for patients with cancer pain

Henrique A. Parsons, Maxine de la Cruz, Badi El Osta et al. · Cancer · 2009 · 90 citations

, , +17

1–5 of 25

Authors

89

  1. ÉB
    Éduardo Bruera

    The University of Texas MD Anderson Cancer Center, United States

    9 publications · 732 citations

    9

    h-index

  2. JS
    Juan Santiago‐Palma

    Memorial Sloan Kettering Cancer Center, United States

    2 publications · 159 citations

    2

    h-index

  3. PL
    Paolo L. Manfredi

    Memorial Sloan Kettering Cancer Center, United States

    2 publications · 159 citations

    2

    h-index

  4. DF
    Daniel Fischberg

    Icahn School of Medicine at Mount Sinai, United States

    2 publications · 159 citations

    2

    h-index

  5. JH
    John Hanson

    University of Alberta, Canada

    2 publications · 323 citations

    2

    h-index

1–5 of 89

Institutions

38

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    5 h-index

    24 publications

    1.6K citations

  2. Grey Nuns Community Hospital

    Edmonton, Canada

    4 h-index

    8 publications

    923 citations

  3. University of Alberta

    Edmonton, Canada

    3 h-index

    5 publications

    434 citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    3 h-index

    14 publications

    1.1K citations

  5. Universidad de La Laguna

    San Cristóbal de La Laguna, Spain

    2 h-index

    3 publications

    168 citations

  6. Royal Perth Hospital

    Perth, Australia

    1 h-index

    1 publications

    33 citations

  7. Mount Sinai Beth Israel

    New York, United States

    1 h-index

    1 publications

    265 citations

  8. Scripps Research Institute

    San Diego, United States

    1 h-index

    1 publications

    10 citations

1–8 of 38

Venues

  1. Journal of Palliative Medicine

    6 publications · 206 citations

    6

    h-index

  2. Cancer

    4 publications · 392 citations

    4

    h-index

  3. Journal of Pain and Symptom Management

    3 publications · 379 citations

    3

    h-index

  4. Pain

    2 publications · 166 citations

    2

    h-index

  5. Pediatric Blood & Cancer

    1 publications · 72 citations

    1

    h-index

1–5