Concepedia

Metallocofactor Function

Metallocofactor Function is a biochemical mechanism denoting the specific catalytic role performed by a metal ion within a metalloenzyme, wherein the metal ion acts as an essential cofactor that facilitates substrate binding, orientation, or chemical transformation through coordination chemistry distinct from the proteinaceous active site residues.

23

Publications

1.7K

Citations

125

Authors

47

Institutions

Publications per year

2017–2026

9

Parents

Publications

23

A Ni-Fe-Cu Center in a Bifunctional Carbon Monoxide Dehydrogenase/ Acetyl-CoA Synthase

Tzanko Doukov, T.M. Iverson, Javier Seravalli et al. · Science · 2002 · 527 citations

, , +17

Structural evidence for a dynamic metallocofactor during N <sub>2</sub> reduction by Mo-nitrogenase

Wonchull Kang, Chi Chung Lee, Andrew J. Jasniewski et al. · Science · 2020 · 181 citations · Full text

, , +17

Mo-, V-, and Fe-Nitrogenases Use a Universal Eight-Electron Reductive-Elimination Mechanism To Achieve N <sub>2</sub> Reduction

Derek F. Harris, Dmitriy Lukoyanov, Hayden Kallas et al. · Biochemistry · 2019 · 137 citations

, , +17

An Active Dimanganese(III)−Tyrosyl Radical Cofactor in <i>Escherichia coli</i> Class Ib Ribonucleotide Reductase

Joseph A. Cotruvo, JoAnne Stubbe · Biochemistry · 2010 · 129 citations · Full text

, , +17

Investigations on the Role of Proton-Coupled Electron Transfer in Hydrogen Activation by [FeFe]-Hydrogenase

David W. Mulder, Michael W. Ratzloff, Maurizio Bruschi et al. · Journal of the American Chemical Society · 2014 · 119 citations

, , +17

1–5 of 23

Authors

125

  1. YH
    Yilin Hu

    University of California, Irvine, United States

    4 publications · 288 citations

    4

    h-index

  2. MW
    Markus W. Ribbe

    University of California, Irvine, United States

    4 publications · 288 citations

    4

    h-index

  3. NS
    Nathaniel S. Sickerman

    University of California, Irvine, United States

    3 publications · 107 citations

    3

    h-index

  4. NJ
    Nicholas J. Cox

    Durham University, United Kingdom

    3 publications · 108 citations

    3

    h-index

  5. WL
    Wolfgang Lubitz

    Max Planck Institute for Chemical Energy Conversion, Germany

    3 publications · 107 citations

    3

    h-index

1–5 of 125

Institutions

47

  1. Massachusetts Institute of Technology

    Cambridge, United States

    5 h-index

    16 publications

    3.3K citations

  2. University of California, Irvine

    Irvine, United States

    4 h-index

    18 publications

    1.4K citations

  3. Montana State University

    Bozeman, United States

    3 h-index

    14 publications

    458 citations

  4. Max Planck Institute for Chemical Energy Conversion

    Mülheim, Germany

    3 h-index

    15 publications

    525 citations

  5. Pennsylvania State University

    State College, United States

    2 h-index

    14 publications

    956 citations

  6. Nagoya University

    Nagoya, Japan

    2 h-index

    8 publications

    276 citations

  7. Stockholm University

    Stockholm, Sweden

    2 h-index

    5 publications

    228 citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    10 publications

    286 citations

1–8 of 47

Venues

  1. Biochemistry

    4 publications · 304 citations

    4

    h-index

  2. Journal of the American Chemical Society

    JACS · 2 publications · 135 citations

    3

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 123 citations

    2

    h-index

  4. Science

    2 publications · 708 citations

    2

    h-index

  5. F1000 Biology Reports

    1 publications · 76 citations

    1

    h-index

1–5