Concepedia

Metabolic Dependency Engineering

Metabolic Dependency Engineering is a biocontainment strategy that introduces engineered metabolic dependencies in genetically modified organisms by designing synthetic auxotrophies for non-natural nutrients, thereby restricting their survival to controlled environments containing those specific factors.

3

Publications

97

Citations

22

Authors

7

Institutions

Publications per year

2017–2026

2

Parents

Publications

3

An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation

Samantha G. Scharenberg, Wentao Dong, Ali Ghoochani et al. · Science Advances · 2023 · 46 citations · Full text

, , +17

Structural and regulatory mutations allowing utilization of citrulline or carbamoylaspartate as a source of carbamoylphosphate in Escherichia coli K-12

Christianne Legrain, Victor Stalon, Nicolas Glansdorff et al. · Journal of Bacteriology · 1976 · 27 citations · Full text

, , +16

Phosphite synthetic auxotrophy as an effective biocontainment strategy for the industrial chassis Pseudomonas putida

Enrique Asin‐Garcia, Christos Batianis, Yunsong Li et al. · Microbial Cell Factories · 2022 · 24 citations · Full text

, , +17

1–3 of 3

Authors

22

  1. MA
    Monther Abu-Remaileh

    Stanford University, United States

    1 publications · 46 citations

    1

    h-index

  2. KS
    Kaitlyn Spees

    Stanford University, United States

    1 publications · 46 citations

    1

    h-index

  3. MC
    M Crabeel

    Vrije Universiteit Brussel, Belgium

    1 publications · 27 citations

    1

    h-index

  4. AR
    Aswini R. Krishnan

    University of California San Diego, United States

    1 publications · 46 citations

    1

    h-index

  5. RL
    Roni Levin‐Konigsberg

    Stanford University, United States

    1 publications · 46 citations

    1

    h-index

1–5 of 22

Institutions

7

  1. Technical University of Denmark

    Kongens Lyngby, Denmark

    1 h-index

    1 publications

    24 citations

  2. Novo Nordisk Foundation

    Copenhagen, Denmark

    1 h-index

    1 publications

    24 citations

  3. Wageningen University & Research

    Wageningen, The Netherlands

    1 h-index

    6 publications

    144 citations

  4. LifeGlimmer (Germany)

    Berlin, Germany

    1 h-index

    1 publications

    24 citations

  5. Stanford University

    Stanford, United States

    1 h-index

    10 publications

    460 citations

  6. Stanford Medicine

    Stanford, United States

    1 h-index

    1 publications

    46 citations

  7. Imperial College London

    London, United Kingdom

    1 h-index

    1 publications

    24 citations

1–7 of 7

Venues

  1. Microbial Cell Factories

    1 publications · 24 citations

    1

    h-index

  2. Science Advances

    1 publications · 46 citations

    1

    h-index

  3. Journal of Bacteriology

    JB · 1 publications · 27 citations

    1

    h-index

1–3