Concepedia

Membrane-active Antibiotics

Membrane-Active Antibiotics is a class of antimicrobial agents that selectively disrupt bacterial membrane integrity or function, distinguishing them from antibiotics targeting intracellular processes by exerting their bactericidal effects through direct interaction with lipid bilayers.

683

Publications

39.7K

Citations

2.8K

Authors

780

Institutions

Publications per year

2017–2026

189

Parents

Publications

683

Use of the Cell Wall Precursor Lipid II by a Pore-Forming Peptide Antibiotic

Eefjan Breukink, I. Wiedemann, Cindy van Kraaij et al. · Science · 1999 · 805 citations · Full text

, , +17

The nisin–lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics

Shang‐Te Danny Hsu, Eefjan Breukink, Eugene Tischenko et al. · Nature Structural & Molecular Biology · 2004 · 544 citations · Full text

, , +12

An Alternative Bactericidal Mechanism of Action for Lantibiotic Peptides That Target Lipid II

Hester E. Hasper, Naomi E. Kramer, Leif Smith et al. · Science · 2006 · 497 citations · Full text

, , +17

Use of the fluorescent probe 1-N-phenylnaphthylamine to study the interactions of aminoglycoside antibiotics with the outer membrane of Pseudomonas aeruginosa

Bernadette A. Loh, Chris W.M. Grant, Robert E. W. Hancock · Antimicrobial Agents and Chemotherapy · 1984 · 487 citations

, , +13

The action of certain antibiotics on mitochondrial, erythrocyte and artificial phospholipid membranes. The role of induced proton permeability

Peter J. F. Henderson, J D McGivan, Joseph Chappell · Biochemical Journal · 1969 · 412 citations · Full text

, , +17

1–5 of 683

Authors

2.8K

  1. JH
    Jayanta Haldar

    Jawaharlal Nehru Centre for Advanced Scientific Research, India

    18 publications · 903 citations

    16

    h-index

  2. SL
    Shouping Liu

    Singapore Eye Research Institute, Singapore

    13 publications · 827 citations

    12

    h-index

  3. SL
    Shuimu Lin

    Guangzhou Medical University, China

    11 publications · 670 citations

    11

    h-index

  4. JL
    Jack L. Strominger

    Harvard University, United States

    10 publications · 558 citations

    10

    h-index

  5. MM
    Mohini Mohan Konai

    Jawaharlal Nehru Centre for Advanced Scientific Research, India

    10 publications · 508 citations

    10

    h-index

1–5 of 2.8K

Institutions

780

  1. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    59 publications

    2.7K citations

  2. Harvard University

    Cambridge, United States

    16 h-index

    38 publications

    3.1K citations

  3. Jawaharlal Nehru Centre for Advanced Scientific Research

    Bengaluru, India

    16 h-index

    77 publications

    4.1K citations

  4. UCLouvain

    Louvain-la-Neuve, Belgium

    15 h-index

    60 publications

    3.1K citations

  5. University of Tübingen

    Tübingen, Germany

    11 h-index

    34 publications

    3.2K citations

  6. Tel Aviv University

    Tel Aviv, Israel

    10 h-index

    53 publications

    3K citations

  7. National University of Singapore

    Singapore, Singapore

    10 h-index

    32 publications

    2K citations

  8. Utrecht University

    Utrecht, The Netherlands

    9 h-index

    44 publications

    12.2K citations

1–8 of 780

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 64 publications · 5K citations

    33

    h-index

  2. Journal of Medicinal Chemistry

    30 publications · 2.3K citations

    27

    h-index

  3. 25

    h-index

  4. Journal of Antimicrobial Chemotherapy

    JAC · 23 publications · 1.1K citations

    18

    h-index

  5. ACS Infectious Diseases

    24 publications · 740 citations

    17

    h-index

1–5