Concepedia

Mechanotransduction Defects

Mechanotransduction Defects is a pathological impairment in the cellular process by which mechanical stimuli are converted into biochemical signals, leading to aberrant cytoskeletal organization and function.

31

Publications

2.2K

Citations

186

Authors

91

Institutions

Publications per year

2017–2026

11

Parents

Publications

31

Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis

Ryan Zarychanski, Vincent Schulz, Brett L. Houston et al. · Blood · 2012 · 453 citations · Full text

, , +6

Genetic dissection of mechanosensory transduction: Mechanoreception-defective mutations of drosophila

Maurice J. Kernan · Neuron · 1994 · 358 citations

, , +14

Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis

Bertrand Coste, Gunnar Houge, Michael F. Murray et al. · Proceedings of the National Academy of Sciences · 2013 · 235 citations · Full text

, , +17

Harmonin Mutations Cause Mechanotransduction Defects in Cochlear Hair Cells

Nicolas Grillet, Wei Xiong, Anna Reynolds et al. · Neuron · 2009 · 158 citations · Full text

, , +14

Selective loss of vagal intramuscular mechanoreceptors in mice mutant for steel factor, the c-Kit receptor ligand

Edward A. Fox, Mardi S. Byerly, Elizabeth A. Baronowsky et al. · Anatomy and Embryology · 2002 · 74 citations

, , +13

1–5 of 31

Authors

186

  1. NG
    Nicolas Grillet

    Scripps Research Institute, United States

    3 publications · 211 citations

    3

    h-index

  2. UM
    Ulrich Müller

    Scripps Research Institute, United States

    3 publications · 213 citations

    3

    h-index

  3. WX
    Wei Xiong

    Tsinghua University, China

    3 publications · 214 citations

    3

    h-index

  4. BK
    Bechara Kachar

    National Institute on Deafness and Other Communication Disorders, United States

    2 publications · 174 citations

    2

    h-index

  5. AP
    Ardem Patapoutian

    Scripps Research Institute, United States

    2 publications · 294 citations

    2

    h-index

1–5 of 186

Institutions

91

  1. Scripps Research Institute

    San Diego, United States

    4 h-index

    17 publications

    1.9K citations

  2. National Institute on Deafness and Other Communication Disorders

    Bethesda, United States

    4 h-index

    9 publications

    469 citations

  3. National Institutes of Health

    Bethesda, United States

    4 h-index

    13 publications

    812 citations

  4. University of Washington

    Seattle, United States

    3 h-index

    11 publications

    277 citations

  5. Radboud University Medical Center

    Nijmegen, The Netherlands

    2 h-index

    3 publications

    265 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    8 publications

    771 citations

  7. University of California San Diego

    San Diego, United States

    2 h-index

    2 publications

    397 citations

  8. Inserm

    Paris, France

    2 h-index

    5 publications

    165 citations

1–8 of 91

Venues

  1. Neuron

    2 publications · 516 citations

    2

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 305 citations

    2

    h-index

  3. Anatomy and Embryology

    2 publications · 144 citations

    2

    h-index

  4. BioEssays

    1 publications · 28 citations

    1

    h-index

  5. The Journal of Sexual Medicine

    1 publications · 64 citations

    1

    h-index

1–5