Concepedia

Mechanosensitive Adhesion Complexes

Mechanosensitive Adhesion Complexes is a specialized type of cell-matrix or cell-cell adhesion structure that dynamically modulates its molecular composition and mechanical stability in response to externally applied or internally generated forces, thereby enabling mechanotransduction at the cellular level.

54

Publications

3.6K

Citations

306

Authors

131

Institutions

Publications per year

2017–2026

23

Parents

Publications

54

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

Ana M. Pasapera, I Schneider, Erin Rericha et al. · The Journal of Cell Biology · 2010 · 577 citations · Full text

, , +17

N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells

Brian D. Cosgrove, Keeley L. Mui, Tristan P. Driscoll et al. · Nature Materials · 2016 · 350 citations · Full text

, , +16

Molecular mechanisms of cellular mechanosensing

Tianzhi Luo, Krithika Mohan, Pablo A. Iglesias et al. · Nature Materials · 2013 · 271 citations · Full text

, , +14

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction

Marcos Sotomayor, Wilhelm A. Weihofen, Rachelle Gaudet et al. · Nature · 2012 · 186 citations · Full text

, , +14

Focal adhesions as mechanosensors: The two-spring model

Ulrich S. Schwarz, Thorsten Erdmann, Ilka B. Bischofs · Biosystems · 2005 · 171 citations

, , +14

1–5 of 54

Authors

306

  1. FM
    Fredrick M. Pavalko

    Indiana University – Purdue University Indianapolis, United States

    2 publications · 49 citations

    3

    h-index

  2. MJ
    Martin J. Humphries

    University of Manchester, United Kingdom

    3 publications · 243 citations

    3

    h-index

  3. TP
    Tristan P. Driscoll

    University of Pennsylvania, United States

    2 publications · 395 citations

    2

    h-index

  4. JD
    Jonathan D. Humphries

    University of Manchester, United Kingdom

    2 publications · 116 citations

    2

    h-index

  5. BT
    Benjamin T. Goult

    University of Kent, United Kingdom

    2 publications · 72 citations

    2

    h-index

1–5 of 306

Institutions

131

  1. Wellcome Centre for Cell-Matrix Research

    Manchester, United Kingdom

    3 h-index

    14 publications

    1.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    17 publications

    1.2K citations

  3. University of Manchester

    Manchester, United Kingdom

    3 h-index

    16 publications

    1.3K citations

  4. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    3 h-index

    7 publications

    191 citations

  5. Indiana University School of Medicine

    Indianapolis, United States

    3 h-index

    6 publications

    160 citations

  6. University of Kent

    Canterbury, United Kingdom

    3 h-index

    7 publications

    235 citations

  7. University of California San Diego

    San Diego, United States

    3 h-index

    3 publications

    653 citations

  8. Stanford University

    Stanford, United States

    3 h-index

    6 publications

    130 citations

1–8 of 131

Venues

  1. Biophysical Journal

    7 publications · 298 citations

    7

    h-index

  2. Journal of Cell Science

    3 publications · 168 citations

    3

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 113 citations

    3

    h-index

  4. Nature

    2 publications · 236 citations

    2

    h-index

  5. FEBS Letters

    2 publications · 23 citations

    2

    h-index

1–5