Concepedia

Maternal Transcript Translation Activation

Maternal Transcript Translation Activation is a regulatory mechanism in early embryonic development wherein dormant maternal messenger RNAs deposited in the oocyte are selectively recruited to ribosomes and initiated into protein synthesis, distinguishing it from other forms of post-transcriptional regulation by its dependence on maternal factors and its occurrence prior to zygotic genome activation.

77

Publications

5.6K

Citations

324

Authors

141

Institutions

Publications per year

2017–2026

16

Parents

Publications

77

SMAUG Is a Major Regulator of Maternal mRNA Destabilization in Drosophila and Its Translation Is Activated by the PAN GU Kinase

Wael Tadros, Aaron L. Goldman, Tomas Babak et al. · Developmental Cell · 2007 · 340 citations · Full text

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Changes in state of adenylation and time course of degradation of maternal mRNAs during oocyte maturation and early embryonic development in the mouse

Barbara V. Paynton, Rachel E. Rempel, Rosemary F. Bachvarova · Developmental Biology · 1988 · 303 citations

, , +17

Smaug Recruits the CCR4/POP2/NOT Deadenylase Complex to Trigger Maternal Transcript Localization in the Early Drosophila Embryo

Jennifer L. Semotok, Ramona L. Cooperstock, Benjamin D. Pinder et al. · Current Biology · 2005 · 263 citations · Full text

, , +12

Coordinate Initiation of <i>Drosophila</i> Development by Regulated Polyadenylation of Maternal Messenger RNAs

Fernando J. Sallés, Marshal E. Lieberfarb, Christopher Wreden et al. · Science · 1994 · 235 citations

, , +17

Sequence-specific adenylations and deadenylations accompany changes in the translation of maternal messenger RNA after fertilization of Spisula oocytes

Éric Rosenthal, Terese R. Tansey, Joan Ruderman et al. · Journal of Molecular Biology · 1983 · 183 citations

, , +16

1–5 of 77

Authors

324

  1. HF
    Heng‐Yu Fan

    Zhejiang University, China

    5 publications · 426 citations

    5

    h-index

  2. MC
    Marco Conti

    Stanford University, United States

    4 publications · 432 citations

    4

    h-index

  3. ES
    Emre Seli

    Yale University, United States

    4 publications · 256 citations

    4

    h-index

  4. DS
    Denny Sakkas

    Boston IVF, United States

    3 publications · 227 citations

    3

    h-index

  5. MD
    Maria D. Lalioti

    Yale University, United States

    3 publications · 227 citations

    3

    h-index

1–5 of 324

Institutions

141

  1. University of California, San Francisco

    San Francisco, United States

    6 h-index

    30 publications

    3.1K citations

  2. Yale University

    New Haven, United States

    6 h-index

    33 publications

    1.8K citations

  3. Zhejiang University

    Hangzhou, China

    5 h-index

    24 publications

    2.1K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    11 publications

    419 citations

  5. Reproductive Science Center

    San Ramon, United States

    4 h-index

    31 publications

    3.7K citations

  6. Broad Center

    Los Angeles, United States

    4 h-index

    28 publications

    3.3K citations

  7. Sir Run Run Shaw Hospital

    Hangzhou, China

    4 h-index

    4 publications

    383 citations

  8. University of Arkansas for Medical Sciences

    Little Rock, United States

    3 h-index

    9 publications

    637 citations

1–8 of 141

Venues

  1. Developmental Biology

    9 publications · 757 citations

    9

    h-index

  2. Development

    8 publications · 596 citations

    8

    h-index

  3. Nucleic Acids Research

    6 publications · 395 citations

    6

    h-index

  4. Journal of Biological Chemistry

    JBC · 4 publications · 209 citations

    4

    h-index

  5. RNA

    3 publications · 150 citations

    3

    h-index

1–5