Concepedia

Lysosomal Cargo Sorting

Lysosomal Cargo Sorting is a cellular trafficking mechanism that directs specific macromolecules and organelles to lysosomes for degradation or recycling by recognizing sorting signals and routing them through vesicular transport pathways distinct from secretory or cytosolic delivery routes.

93

Publications

7.4K

Citations

483

Authors

176

Institutions

Publications per year

2017–2026

15

Parents

Publications

93

Enhanced Degradation of EGF Receptors by a Sorting Nexin, SNX1

Richard C. Kurten, Deborah L. Cadena, Gordon N. Gill · Science · 1996 · 386 citations

, , +17

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

Karianne E. Longva, Frøydis D. Blystad, Espen Stang et al. · The Journal of Cell Biology · 2002 · 381 citations · Full text

, , +17

The Niemann-Pick C1 Protein Resides in a Vesicular Compartment Linked to Retrograde Transport of Multiple Lysosomal Cargo

Edward B. Neufeld, Meryl E. Wastney, Shutish C. Patel et al. · Journal of Biological Chemistry · 1999 · 375 citations · Full text

, , +17

Modulation of Postendocytic Sorting of G Protein-Coupled Receptors

Jennifer L. Whistler, Johan Enquist, Aaron Marley et al. · Science · 2002 · 322 citations

, , +17

Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

Peter Lobel, K Fujimoto, Richard D. Ye et al. · Cell · 1989 · 273 citations

, , +16

1–5 of 93

Authors

483

  1. JT
    JoAnn Trejo

    University of California San Diego, United States

    7 publications · 679 citations

    7

    h-index

  2. CR
    Carlos R. Morales

    McGill University, Canada

    5 publications · 250 citations

    5

    h-index

  3. HL
    Huilan Lin

    University of California San Diego, United States

    3 publications · 183 citations

    3

    h-index

  4. MR
    Michael R. Dores

    University of California San Diego, United States

    3 publications · 196 citations

    3

    h-index

  5. SL
    Stéphane Lefrançois

    McGill University, Canada

    3 publications · 132 citations

    3

    h-index

1–5 of 483

Institutions

176

  1. National Institutes of Health

    Bethesda, United States

    6 h-index

    17 publications

    3.9K citations

  2. McGill University

    Montreal, Canada

    5 h-index

    14 publications

    704 citations

  3. Washington University in St. Louis

    St Louis, United States

    5 h-index

    14 publications

    3.1K citations

  4. University of California San Diego

    San Diego, United States

    5 h-index

    20 publications

    2.2K citations

  5. Inserm

    Paris, France

    4 h-index

    12 publications

    1.1K citations

  6. University of Cambridge

    Cambridge, United Kingdom

    4 h-index

    8 publications

    492 citations

  7. Harvard University

    Cambridge, United States

    4 h-index

    15 publications

    652 citations

  8. University College London

    London, United Kingdom

    4 h-index

    9 publications

    449 citations

1–8 of 176

Venues

  1. Journal of Biological Chemistry

    JBC · 17 publications · 1.4K citations

    17

    h-index

  2. Molecular Biology of the Cell

    MBC · 14 publications · 1.3K citations

    14

    h-index

  3. Traffic

    10 publications · 497 citations

    10

    h-index

  4. Journal of Cell Science

    8 publications · 629 citations

    8

    h-index

  5. The Journal of Cell Biology

    JCB · 5 publications · 879 citations

    5

    h-index

1–5