Concepedia

Lymphatic Vessel Normalization

Lymphatic Vessel Normalization is a therapeutic strategy in vascular biology that refers to the process of restoring structurally and functionally aberrant lymphatic vessels to a morphologically and physiologically balanced state, thereby improving fluid drainage, immune cell trafficking, and tissue homeostasis within the tumor or inflamed microenvironment.

11

Publications

1.5K

Citations

125

Authors

36

Institutions

Publications per year

2017–2026

6

Parents

Publications

11

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF

Charlotte Rolny, Massimiliano Mazzone, Sònia Tugues et al. · Cancer Cell · 2011 · 702 citations · Full text

, , +16

De novo induction of intratumoral lymphoid structures and vessel normalization enhances immunotherapy in resistant tumors

Anna Johansson, Bo He, Zhi-Jie Li et al. · Nature Immunology · 2017 · 321 citations

, , +16

Targeting Activin Receptor-Like Kinase 1 Inhibits Angiogenesis and Tumorigenesis through a Mechanism of Action Complementary to Anti-VEGF Therapies

Dana D. Hu‐Lowe, Enhong Chen, Lianglin Zhang et al. · Cancer Research · 2011 · 133 citations · Full text

, , +17

Lymph Node Transfer and Perinodal Lymphatic Growth Factor Treatment for Lymphedema

Krista Honkonen, Mikko Visuri, Tomi V. Tervala et al. · Annals of Surgery · 2012 · 101 citations

, , +16

CXCL10 mediates CD8+ T cells to facilitate vessel normalization and improve the efficacy of cetuximab combined with PD-1 checkpoint inhibitors in colorectal cancer

Wei Yan, Lin Qiu, Meiling Yang et al. · Cancer Letters · 2023 · 62 citations

, , +17

1–5 of 11

Authors

125

  1. CR
    Charlotte Rolny

    Karolinska Institutet, Sweden

    1 publications · 702 citations

    1

    h-index

  2. DR
    David R. Shalinsky

    Pfizer (United States), United States

    1 publications · 133 citations

    1

    h-index

  3. ST
    Sònia Tugues

    University of Zurich, Switzerland

    1 publications · 702 citations

    1

    h-index

  4. HD
    Henrik Daa Schrøder

    Odense University Hospital, Denmark

    1 publications · 14 citations

    1

    h-index

  5. WF
    Walter Fiedler

    Universität Hamburg, Germany

    1 publications · 133 citations

    1

    h-index

1–5 of 125

Institutions

36

  1. University of Rochester

    Rochester, United States

    2 h-index

    21 publications

    1K citations

  2. Boston Children's Hospital

    Boston, United States

    1 h-index

    1 publications

    30 citations

  3. Nanfang Hospital

    Guangzhou, China

    1 h-index

    8 publications

    496 citations

  4. The University of Western Australia

    Perth, Australia

    1 h-index

    7 publications

    2.2K citations

  5. First Affiliated Hospital of Jinan University

    Guangzhou, China

    1 h-index

    1 publications

    62 citations

  6. Cooper Medical School of Rowan University

    Camden, United States

    1 h-index

    2 publications

    110 citations

  7. Bryan College

    Dayton, United States

    1 h-index

    3 publications

    90 citations

  8. Unimed Medical Institute

    Hong Kong, China

    1 h-index

    3 publications

    69 citations

1–8 of 36

Venues

  1. Scientific Reports

    1 publications · 30 citations

    1

    h-index

  2. Nature Aging

    1 publications · 47 citations

    1

    h-index

  3. Cancer Cell

    1 publications · 702 citations

    1

    h-index

  4. Regenerative Medicine

    1 publications · 58 citations

    1

    h-index

  5. Journal of Plastic Surgery and Hand Surgery

    1 publications · 14 citations

    1

    h-index

1–5