Concepedia

Looping Thermodynamics

Looping Thermodynamics is a theoretical framework that characterizes the energetic stability and conformational entropy of DNA loops formed through protein-mediated interactions, distinguishing it from general nucleic acid thermodynamics by focusing on the free energy penalties and looping probability as a function of loop length, flexibility, and architectural protein binding constraints.

84

Publications

3.9K

Citations

216

Authors

100

Institutions

Publications per year

2017–2026

4

Parents

Publications

84

Transproteomic evidence of a loop-deletion mechanism for enhancing protein thermostability

Michael J. Thompson, David Eisenberg · Journal of Molecular Biology · 1999 · 299 citations

, , +16

Knotting of a DNA Chain During Ring Closure

Stanley Y. Shaw, James C. Wang · Science · 1993 · 293 citations

, , +12

DNA Looping and Physical Constraints on Transcription Regulation

José M. G. Vilar, Stanislas Leibler · Journal of Molecular Biology · 2003 · 193 citations

, , +16

Thermodynamic and spectroscopic study of bulge loops in oligoribonucleotides

Carl E. Longfellow, Ryszard Kierzek, Douglas H. Turner · Biochemistry · 1990 · 152 citations

, , +17

Interplay between DNA sequence and negative superhelicity drives R-loop structures

Robert Stolz, Shaheen Sulthana, Stella R. Hartono et al. · Proceedings of the National Academy of Sciences · 2019 · 135 citations · Full text

, , +14

1–5 of 84

Authors

216

  1. JM
    José M. G. Vilar

    Universitat de Barcelona, Spain

    4 publications · 329 citations

    4

    h-index

  2. JD
    Jason D. Kahn

    University of Maryland, College Park, United States

    4 publications · 203 citations

    4

    h-index

  3. LF
    Laura Finzi

    Emory University, United States

    4 publications · 120 citations

    4

    h-index

  4. LS
    Leonor Saiz

    University of Pennsylvania, United States

    3 publications · 136 citations

    3

    h-index

  5. DD
    David Dunlap

    Emory University, United States

    3 publications · 102 citations

    3

    h-index

1–5 of 216

Institutions

100

  1. Emory University

    Atlanta, United States

    4 h-index

    19 publications

    614 citations

  2. University of Maryland, College Park

    College Park, United States

    4 h-index

    15 publications

    788 citations

  3. University of Rochester

    Rochester, United States

    4 h-index

    9 publications

    352 citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    3 h-index

    6 publications

    272 citations

  5. California Institute of Technology

    Pasadena, United States

    3 h-index

    8 publications

    299 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    4 publications

    220 citations

  7. Georgia Institute of Technology

    Atlanta, United States

    2 h-index

    4 publications

    78 citations

  8. University of Illinois Chicago

    Chicago, United States

    2 h-index

    4 publications

    140 citations

1–8 of 100

Venues

  1. Journal of Molecular Biology

    JMB · 11 publications · 838 citations

    11

    h-index

  2. Biophysical Journal

    10 publications · 432 citations

    10

    h-index

  3. Biochemistry

    8 publications · 399 citations

    8

    h-index

  4. Nucleic Acids Research

    8 publications · 377 citations

    8

    h-index

  5. Physical Review Letters

    PRL · 5 publications · 153 citations

    5

    h-index

1–5