Concepedia

Loop Energy Minimization

Loop Energy Minimization is an optimization method in computational structural biology that refines predicted protein loop conformations by iteratively adjusting their dihedral angles to reduce the overall potential energy of the loop region, thereby achieving thermodynamically stable structures consistent with the surrounding protein framework.

46

Publications

7K

Citations

136

Authors

74

Institutions

Publications per year

2017–2026

4

Parents

Publications

46

A hierarchical approach to all‐atom protein loop prediction

Matthew P. Jacobson, David L. Pincus, Chaya S. Rapp et al. · Proteins Structure Function and Bioinformatics · 2004 · 2.5K citations

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Modeling of loops in protein structures

András Fiser, Richard Kinh Gian, Andrej Šali · Protein Science · 2000 · 2.2K citations · Full text

, , +17

Predicting antibody hypervariable loop conformation. I. Ensembles of random conformations for ringlike structures

Peter S. Shenkin, David L. Yarmush, Richard Fine et al. · Biopolymers · 1987 · 250 citations

, , +17

The Combination of Symbolic and Numerical Computation or Three-Dimensional Modeling of RNA

François Major, Marcel Turcotte, Daniel Gautheret et al. · Science · 1991 · 182 citations

, , +17

Fast evaluation of internal loops in RNA secondary structure prediction.

R B Lyngs√∏, Michael Zuker, Clara Nautrup Pedersen · Bioinformatics · 1999 · 146 citations · Full text

, , +17

1–5 of 46

Authors

136

  1. RA
    Richard A. Friesner

    Columbia University, United States

    5 publications · 2.8K citations

    5

    h-index

  2. HM
    Hagai Meirovitch

    Florida State University, United States

    4 publications · 93 citations

    4

    h-index

  3. KZ
    Kai Zhu

    Schrodinger (United States), United States

    4 publications · 261 citations

    4

    h-index

  4. HA
    Harold A. Scheraga

    Cornell University, United States

    3 publications · 83 citations

    3

    h-index

  5. SZ
    Suwen Zhao

    ShanghaiTech University, China

    2 publications · 160 citations

    2

    h-index

1–5 of 136

Institutions

74

  1. Columbia University

    New York, United States

    7 h-index

    23 publications

    9.9K citations

  2. Cornell University

    Ithaca, United States

    4 h-index

    8 publications

    214 citations

  3. Schrodinger (United States)

    New York, United States

    3 h-index

    5 publications

    5.3K citations

  4. Wright State University

    Dayton, United States

    2 h-index

    2 publications

    126 citations

  5. University of Pittsburgh

    Pittsburgh, United States

    2 h-index

    4 publications

    92 citations

  6. Yeshiva University

    New York, United States

    2 h-index

    3 publications

    2.6K citations

  7. Princeton University

    Princeton, United States

    2 h-index

    4 publications

    136 citations

  8. Florida State University

    Tallahassee, United States

    2 h-index

    3 publications

    70 citations

1–8 of 74

Venues

  1. Proteins Structure Function and Bioinformatics

    11 publications · 3K citations

    11

    h-index

  2. Biopolymers

    4 publications · 342 citations

    4

    h-index

  3. Journal of Computational Chemistry

    3 publications · 72 citations

    3

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 94 citations

    2

    h-index

  5. Journal of High Energy Physics

    JHEP · 1 publications · 94 citations

    1

    h-index

1–5