Concepedia

Loop Conformational Search

Loop Conformational Search is a computational method in structural biology that systematically explores the space of possible three-dimensional arrangements of amino acid residues in protein loops to identify energetically favorable and sterically feasible conformations consistent with the surrounding protein structure.

35

Publications

2.2K

Citations

88

Authors

52

Institutions

Publications per year

2017–2026

1

Parents

Publications

35

LowModeMD—Implicit Low-Mode Velocity Filtering Applied to Conformational Search of Macrocycles and Protein Loops

Paul Labute · Journal of Chemical Information and Modeling · 2010 · 337 citations · Full text

, , +17

Conformational sampling using high‐temperature molecular dynamics

Robert E. Bruccoleri, Martin Karplus · Biopolymers · 1990 · 218 citations

, , +11

Structure of antibody hypervariable loops reproduced by a conformational search algorithm

Robert E. Bruccoleri, Edgar Haber, Jiří Novotný · Nature · 1988 · 198 citations

, , +11

High-resolution design of a protein loop

Xiaozhen Hu, Huanchen Wang, Hengming Ke et al. · Proceedings of the National Academy of Sciences · 2007 · 126 citations · Full text

, , +15

Evaluation of the conformational free energies of loops in proteins

Kenneth Smith, Barry Honig · Proteins Structure Function and Bioinformatics · 1994 · 112 citations

, , +17

1–5 of 35

Authors

88

  1. RE
    Robert E. Bruccoleri

    Bristol-Myers Squibb (United States), United States

    4 publications · 442 citations

    4

    h-index

  2. KT
    Kirsi Tappura

    VTT Technical Research Centre of Finland, Finland

    2 publications · 41 citations

    2

    h-index

  3. CD
    Charles DeLisi

    Boston University, United States

    2 publications · 87 citations

    2

    h-index

  4. HM
    Hagai Meirovitch

    Florida State University, United States

    2 publications · 47 citations

    2

    h-index

  5. KS
    Kenneth Smith

    Columbia University, United States

    2 publications · 216 citations

    2

    h-index

1–5 of 88

Institutions

52

  1. Columbia University

    New York, United States

    3 h-index

    11 publications

    914 citations

  2. Soongsil University

    Seoul, South Korea

    2 h-index

    5 publications

    459 citations

  3. Boston University

    Boston, United States

    2 h-index

    7 publications

    327 citations

  4. University of Massachusetts Boston

    Boston, United States

    2 h-index

    2 publications

    87 citations

  5. Harvard University

    Cambridge, United States

    2 h-index

    4 publications

    832 citations

  6. VTT Technical Research Centre of Finland

    Espoo, Finland

    2 h-index

    3 publications

    62 citations

  7. Old Dominion University

    Norfolk, United States

    1 h-index

    1 publications

    66 citations

  8. Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

    Prague, Czechia

    1 h-index

    2 publications

    88 citations

1–8 of 52

Venues

  1. Proteins Structure Function and Bioinformatics

    7 publications · 353 citations

    7

    h-index

  2. Journal of Computational Chemistry

    4 publications · 163 citations

    4

    h-index

  3. Nature

    2 publications · 210 citations

    2

    h-index

  4. Nucleic Acids Research

    2 publications · 177 citations

    2

    h-index

  5. Protein Engineering Design and Selection

    PEDS · 2 publications · 55 citations

    2

    h-index

1–5