Concepedia

Lomustine Therapy

Lomustine Therapy is a chemotherapeutic regimen classified under alkylating agent-based pharmacotherapy, distinguished by its use of lomustine, a nitrosourea compound that crosses the blood-brain barrier to exert cytotoxic effects on malignant glioma cells through DNA alkylation and carbamoylation mechanisms.

207

Publications

20.3K

Citations

1.4K

Authors

512

Institutions

Publications per year

2017–2026

50

Parents

Publications

207

Specific Genetic Predictors of Chemotherapeutic Response and Survival in Patients With Anaplastic Oligodendrogliomas

J. Gregory Cairncross, Keisuke Ueki, Magdelena C. Zlatescu et al. · JNCI Journal of the National Cancer Institute · 1998 · 1.6K citations · Full text

, , +13

Adjuvant Procarbazine, Lomustine, and Vincristine Chemotherapy in Newly Diagnosed Anaplastic Oligodendroglioma: Long-Term Follow-Up of EORTC Brain Tumor Group Study 26951

Martin J. van den Bent, Alba A. Brandes, Martin Taphoorn et al. · Journal of Clinical Oncology · 2012 · 1.2K citations · Full text

, , +17

Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma

Jan C. Buckner, Edward G. Shaw, Stephanie L. Pugh et al. · New England Journal of Medicine · 2016 · 1K citations · Full text

, , +16

Lomustine and Bevacizumab in Progressive Glioblastoma

Wolfgang Wick, Thierry Gorlia, Martin Bendszus et al. · New England Journal of Medicine · 2017 · 978 citations · Full text

, , +17

NOA-04 Randomized Phase III Trial of Sequential Radiochemotherapy of Anaplastic Glioma With Procarbazine, Lomustine, and Vincristine or Temozolomide

Wolfgang Wick, Christian Hartmann, Corinna Engel et al. · Journal of Clinical Oncology · 2009 · 807 citations

, , +16

1–5 of 207

Authors

1.4K

  1. MJ
    Martin J. van den Bent

    Erasmus MC Cancer Institute, Netherlands

    22 publications · 5.2K citations

    19

    h-index

  2. WW
    Wolfgang Wick

    Heidelberg University, Germany

    20 publications · 4.1K citations

    17

    h-index

  3. MW
    Michael Weller

    University Hospital of Zurich, Switzerland

    18 publications · 3.9K citations

    16

    h-index

  4. AA
    Alba A. Brandes

    Istituti di Ricovero e Cura a Carattere Scientifico, Italy

    16 publications · 3.3K citations

    14

    h-index

  5. JP
    Joachim P. Steinbach

    Goethe University Frankfurt, Germany

    11 publications · 1.4K citations

    11

    h-index

1–5 of 1.4K

Institutions

512

  1. Heidelberg University

    Heidelberg, Germany

    19 h-index

    214 publications

    72.3K citations

  2. University Hospital Heidelberg

    Heidelberg, Germany

    15 h-index

    146 publications

    35.2K citations

  3. German Cancer Research Center

    Heidelberg, Germany

    13 h-index

    63 publications

    13.2K citations

  4. Sorbonne Université

    Paris, France

    12 h-index

    22 publications

    4.2K citations

  5. The University of Texas MD Anderson Cancer Center

    Houston, United States

    11 h-index

    65 publications

    6.2K citations

  6. Medisch Centrum Haaglanden

    The Hague, The Netherlands

    11 h-index

    12 publications

    3K citations

  7. Goethe University Frankfurt

    Frankfurt am Main, Germany

    10 h-index

    53 publications

    8.6K citations

  8. University Hospital of Zurich

    Zurich, Switzerland

    9 h-index

    20 publications

    3K citations

1–8 of 512

Venues

  1. Journal of Clinical Oncology

    30 publications · 6.2K citations

    26

    h-index

  2. Cancer

    12 publications · 709 citations

    12

    h-index

  3. PubMed

    Repository · 18 publications · 719 citations

    12

    h-index

  4. Neuro-Oncology

    11 publications · 987 citations

    11

    h-index

  5. Journal of Veterinary Internal Medicine

    JVIM · 9 publications · 560 citations

    9

    h-index

1–5