Concepedia

Locus Control Regions

Locus Control Regions is a cis-regulatory element that functions as a genomic locus conferring high-level, position-independent, and copy number-dependent expression of linked genes by establishing an open chromatin domain.

419

Publications

37.3K

Citations

1.7K

Authors

498

Institutions

Publications per year

2017–2026

19

Variants

Lcrs

Parents

Publications

419

The accessible chromatin landscape of the human genome

Robert E. Thurman, Eric Rynes, Richard Humbert et al. · Nature · 2012 · 2.9K citations · Full text

, , +17

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.

Paolo Moi, Isadora Asunis, Antonio Cao et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations

, , +17

Controlling Elements and the Gene

Barbara McClintock · Cold Spring Harbor Symposia on Quantitative Biology · 1956 · 856 citations

, , +7

DNase-seq: A High-Resolution Technique for Mapping Active Gene Regulatory Elements across the Genome from Mammalian Cells

Lingyun Song, Gregory E. Crawford · Cold Spring Harbor Protocols · 2010 · 664 citations

, , +16

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

Ronghua Lu, Judy C. Chang, Yuet Wai Kan · Proceedings of the National Academy of Sciences · 1996 · 650 citations · Full text

, , +12

1–5 of 419

Authors

1.7K

  1. MG
    Mark Groudine

    Fred Hutch Cancer Center, United States

    18 publications · 2.8K citations

    17

    h-index

  2. NE
    Nancy E. Cooke

    University of Pennsylvania, United States

    16 publications · 1K citations

    15

    h-index

  3. SA
    Stephen A. Liebhaber

    University of Pennsylvania, United States

    16 publications · 1K citations

    15

    h-index

  4. GS
    George Stamatoyannopoulos

    University of Washington Medical Center, United States

    13 publications · 3.5K citations

    13

    h-index

  5. JB
    Jörg Bungert

    University of Florida, United States

    12 publications · 853 citations

    12

    h-index

1–5 of 1.7K

Institutions

498

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    26 h-index

    86 publications

    11.7K citations

  2. University of Washington

    Seattle, United States

    24 h-index

    123 publications

    133.2K citations

  3. National Institutes of Health

    Bethesda, United States

    23 h-index

    90 publications

    8.1K citations

  4. University of Washington Medical Center

    Seattle, United States

    22 h-index

    87 publications

    40.1K citations

  5. Fred Hutch Cancer Center

    Seattle, United States

    20 h-index

    84 publications

    19.3K citations

  6. University of Pennsylvania

    Philadelphia, United States

    20 h-index

    93 publications

    7K citations

  7. Harvard University

    Cambridge, United States

    16 h-index

    43 publications

    8.4K citations

  8. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    16 h-index

    38 publications

    3.7K citations

1–8 of 498

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 54 publications · 7.6K citations

    41

    h-index

  2. Molecular and Cellular Biology

    MCB · 59 publications · 4.5K citations

    40

    h-index

  3. Journal of Biological Chemistry

    JBC · 30 publications · 1.7K citations

    25

    h-index

  4. Nucleic Acids Research

    30 publications · 1.5K citations

    21

    h-index

  5. The Journal of Immunology

    JI · 16 publications · 755 citations

    15

    h-index

1–5