Concepedia

Loading Dose Scheduling

Loading Dose Scheduling is a pharmacokinetic dosing strategy that refers to the administration of an initial higher dose of a drug to rapidly achieve therapeutic plasma concentrations, distinguishing it from maintenance dose scheduling by its intent to quickly attain steady-state levels.

16

Publications

962

Citations

110

Authors

32

Institutions

Publications per year

2017–2026

2

Parents

Publications

16

A Phase I Trial of Perifosine (NSC 639966) on a Loading Dose/Maintenance Dose Schedule in Patients with Advanced Cancer

Lynn Van Ummersen, Kim Binger, Jennifer Volkman et al. · Clinical Cancer Research · 2004 · 157 citations

, , +14

Suramin, an Active Drug for Prostate Cancer: Interim Observations in a Phase I Trial

Mario A. Eisenberger, L. M. Reyno, D. I. Jodrell et al. · JNCI Journal of the National Cancer Institute · 1993 · 131 citations

, , +17

Three-year controlled, randomized trial of the effect of dose-specified loading and strengthening exercises on bone mineral density of spine and femur in nonathletic, physically active women

Mehrsheed Sinaki, Heinz W. Wahner, Erik J. Bergstralh et al. · Bone · 1996 · 105 citations

, , +16

Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy

Inna Y. Gong, Rommel G. Tirona, Ute I. Schwarz et al. · Blood · 2011 · 94 citations

, , +16

Clinical pharmacology of tamoxifen in patients with breast cancer: Correlation with clinical data

Carol J. Fabian, Larry A. Sternson, Moustafa El-serafi et al. · Cancer · 1981 · 85 citations

, , +17

1–5 of 16

Authors

110

  1. RJ
    R J Fergusson

    Western General Hospital, United Kingdom

    1 publications · 12 citations

    1

    h-index

  2. JY
    Jason Yarbrough

    University of Tennessee at Knoxville, United States

    1 publications · 42 citations

    1

    h-index

  3. TJ
    Thomas J. Doherty

    University of Tennessee at Knoxville, United States

    1 publications · 42 citations

    1

    h-index

  4. SL
    Samantha LaRue

    University of Ottawa, Canada

    1 publications · 94 citations

    1

    h-index

  5. AW
    A W Logie

    University of Aberdeen, United Kingdom

    1 publications · 12 citations

    1

    h-index

1–5 of 110

Institutions

32

  1. Mayo Clinic in Arizona

    Scottsdale, United States

    1 h-index

    1 publications

    105 citations

  2. Semmelweis University

    Budapest, Hungary

    1 h-index

    4 publications

    48 citations

  3. Spanish Oncology Genitourinary Group

    Madrid, Spain

    1 h-index

    1 publications

    157 citations

  4. Nihon University

    Tokyo, Japan

    1 h-index

    1 publications

    32 citations

  5. University of Kansas Medical Center

    Kansas City, United States

    1 h-index

    5 publications

    425 citations

  6. Chelsea and Westminster Hospital

    London, United Kingdom

    1 h-index

    4 publications

    44 citations

  7. Ospedale Civile di Venezia

    Venice, Italy

    1 h-index

    1 publications

    29 citations

  8. University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center

    Baltimore, United States

    1 h-index

    8 publications

    1K citations

1–8 of 32

Venues

  1. The Veterinary Journal

    1 publications · 42 citations

    1

    h-index

  2. Cancer

    1 publications · 85 citations

    1

    h-index

  3. Scottish Medical Journal

    SCM · 1 publications · 12 citations

    1

    h-index

  4. JNCI Journal of the National Cancer Institute

    1 publications · 131 citations

    1

    h-index

  5. Bone

    1 publications · 105 citations

    1

    h-index

1–5