Concepedia

Linear Epitope Design

Linear Epitope Design is a computational or experimental methodology within antigen design that specifically identifies and engineers continuous amino acid sequences capable of eliciting targeted immune responses by distinguishing them from conformational or discontinuous epitopes through their primary structural linearity.

27

Publications

825

Citations

177

Authors

70

Institutions

Publications per year

2017–2026

4

Parents

Publications

27

Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope

Mihai L. Azoitei, Yih‐En Andrew Ban, Jean‐Philippe Julien et al. · Journal of Molecular Biology · 2011 · 103 citations · Full text

, , +17

Design And Synthesis of a Novel Potent Myelin Basic Protein Epitope 87−99 Cyclic Analogue:  Enhanced Stability and Biological Properties of Mimics Render Them a Potentially New Class of Immunomodulators

John Matsoukas, Vasso Apostolopoulos, Hubert Kalbacher et al. · Journal of Medicinal Chemistry · 2005 · 71 citations

, , +16

Fine Mapping of a C-Terminal Linear Epitope Highly Conserved among the Major Envelope Glycoprotein E2 (gp51 to gp54) of Different Pestiviruses

Meng Yu, Lin‐Fa Wang, Brian J. Shiell et al. · Virology · 1996 · 54 citations

, , +17

Structure−affinity relationships in the gp41 ELDKWA epitope for the HIV‐1 neutralizing monoclonal antibody 2F5: effects of side‐chain and backbone modifications and conformational constraints

Yu‐Shi Tian, C.V. Ramesh, Xiaolin Ma et al. · Journal of Peptide Research · 2002 · 54 citations

, , +17

Linear B-cell epitope mapping of MAPK3 and MAPK4 from Leishmania braziliensis: implications for the serodiagnosis of human and canine leishmaniasis

Daniel Menezes‐Souza, Tiago Antônio de Oliveira Mendes, Ana Carolina de Araújo Leão et al. · Applied Microbiology and Biotechnology · 2014 · 50 citations

, , +16

1–5 of 27

Authors

177

  1. XW
    Xianwei Wang

    Nanjing Agricultural University, China

    1 publications · 25 citations

    1

    h-index

  2. PL
    Ping Luo

    University of Hong Kong, Hong Kong SAR China

    1 publications · 11 citations

    1

    h-index

  3. OS
    Olga Serup Andersen

    Aarhus University, Denmark

    1 publications · 17 citations

    1

    h-index

  4. JJ
    Jean‐Philippe Julien

    University of Toronto, Canada

    1 publications · 103 citations

    1

    h-index

  5. JP
    Jair P. Cunha-Júnior

    Universidade Federal de Uberlândia, Brazil

    1 publications · 36 citations

    1

    h-index

1–5 of 177

Institutions

70

  1. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    11 publications

    266 citations

  2. Universidade Federal de Uberlândia

    Uberlândia, Brazil

    2 h-index

    10 publications

    374 citations

  3. Universidade Federal de Minas Gerais

    Belo Horizonte, Brazil

    2 h-index

    10 publications

    345 citations

  4. Indian Institute of Science Bangalore

    Bengaluru, India

    1 h-index

    1 publications

    48 citations

  5. Modélisation et Ingénierie des Systèmes Complexes Biologiques pour le Diagnostic

    Montpellier, France

    1 h-index

    2 publications

    58 citations

  6. Biologie et Génétique des Interactions Plante-Parasite

    Montpellier, France

    1 h-index

    2 publications

    40 citations

  7. University of Groningen

    Groningen, The Netherlands

    1 h-index

    1 publications

    11 citations

  8. Ontario Institute for Cancer Research

    Toronto, Canada

    1 h-index

    2 publications

    206 citations

1–8 of 70

Venues

  1. Virology

    4 publications · 134 citations

    4

    h-index

  2. Vaccine

    2 publications · 26 citations

    2

    h-index

  3. Molecular Immunology

    2 publications · 40 citations

    2

    h-index

  4. Veterinary Microbiology

    2 publications · 73 citations

    2

    h-index

  5. Journal of Immunological Methods

    2 publications · 40 citations

    2

    h-index

1–5