Concepedia

Linc Complex-mediated Positioning

LINC Complex-Mediated Positioning is a molecular mechanism of nuclear positioning that specifically involves the linker of nucleoskeleton and cytoskeleton (LINC) complex, distinguishing it from other nuclear positioning mechanisms by its reliance on conserved transmembrane proteins that span the nuclear envelope to mechanically couple the nucleus to cytoskeletal elements for directed intracellular movement.

24

Publications

1.4K

Citations

132

Authors

71

Institutions

Publications per year

2017–2026

14

Parents

Publications

24

Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes

Farhana Haque, Daniela Mazzeo, Jennifer T. Patel et al. · Journal of Biological Chemistry · 2009 · 283 citations · Full text

, , +17

Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts

Wakam Chang, Susumu Antoku, Cecilia Östlund et al. · Nucleus · 2015 · 107 citations · Full text

, , +17

Centrifugal Displacement of Nuclei Reveals Multiple LINC Complex Mechanisms for Homeostatic Nuclear Positioning

Ruijun Zhu, Susumu Antoku, Gregg G. Gundersen · Current Biology · 2017 · 100 citations · Full text

, , +14

The nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts

Samer G. Alam, David B. Lovett, Dae In Kim et al. · Journal of Cell Science · 2015 · 83 citations · Full text

, , +17

Sun-mediated mechanical LINC between nucleus and cytoskeleton regulates βcatenin nuclear access

Gunes Uzer, Guniz Bas, Buer Sen et al. · Journal of Biomechanics · 2018 · 76 citations

, , +16

1–5 of 24

Authors

132

  1. DA
    Daniel A. Starr

    University of California, Davis, United States

    3 publications · 112 citations

    3

    h-index

  2. SA
    Susumu Antoku

    Columbia University, United States

    3 publications · 235 citations

    3

    h-index

  3. GG
    Gregg G. Gundersen

    Columbia University, United States

    3 publications · 235 citations

    3

    h-index

  4. MA
    Manfred Alsheimer

    University of Würzburg, Germany

    2 publications · 42 citations

    2

    h-index

  5. BB
    Brian Burke

    Institute of Medical Biology, Singapore

    2 publications · 77 citations

    2

    h-index

1–5 of 132

Institutions

71

  1. University of California, Davis

    Davis, United States

    3 h-index

    11 publications

    478 citations

  2. Columbia University

    New York, United States

    3 h-index

    11 publications

    919 citations

  3. New York Proton Center

    New York, United States

    2 h-index

    8 publications

    619 citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    9 publications

    642 citations

  5. University of Würzburg

    Würzburg, Germany

    2 h-index

    5 publications

    108 citations

  6. Institute of Medical Biology

    Singapore, Singapore

    2 h-index

    9 publications

    357 citations

  7. Harvard Stem Cell Institute

    Cambridge, United States

    1 h-index

    2 publications

    116 citations

  8. Florida State University

    Tallahassee, United States

    1 h-index

    4 publications

    160 citations

1–8 of 71

Venues

  1. Current Biology

    2 publications · 168 citations

    2

    h-index

  2. The Journal of Cell Biology

    JCB · 2 publications · 140 citations

    2

    h-index

  3. Cell Cycle

    2 publications · 46 citations

    2

    h-index

  4. Nucleus

    2 publications · 147 citations

    2

    h-index

  5. Nature Communications

    1 publications · 69 citations

    1

    h-index

1–5