Concepedia

Leydig Cell Differentiation

Leydig Cell Differentiation is a developmental biological process in which progenitor cells within the fetal testis commit to and acquire the morphological, biochemical, and functional characteristics of steroidogenically active Leydig cells, thereby enabling androgen biosynthesis essential for male phenotypic sex differentiation.

693

Publications

35.3K

Citations

2.5K

Authors

718

Institutions

Publications per year

2017–2026

137

Parents

Publications

693

Characterization of Several Clonal Lines of Cultured Ley dig Tumor Cells: Gonadotropin Receptors and Steroidogenic Responses*

Mario Ascoli · Endocrinology · 1981 · 593 citations

, , +17

Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate

Jane S. Fisher · Human Reproduction · 2003 · 545 citations · Full text

, , +17

Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis

Humphrey Hung‐Chang Yao, Wendy Whoriskey, Blanche Capel · Genes & Development · 2002 · 532 citations · Full text

, , +14

Desert hedgehog (Dhh) Gene Is Required in the Mouse Testis for Formation of Adult-Type Leydig Cells and Normal Development of Peritubular Cells and Seminiferous Tubules

Ann M. Clark, Kristin K. Garland, Lonnie D. Russell · Biology of Reproduction · 2000 · 439 citations

, , +15

<i>Pdgfr-α</i>mediates testis cord organization and fetal Leydig cell development in the XY gonad

Jennifer Brennan, Christopher Tilmann, Blanche Capel · Genes & Development · 2003 · 408 citations · Full text

, , +17

1–5 of 693

Authors

2.5K

  1. RG
    Ren‐Shan Ge

    Wenzhou Medical University, China

    74 publications · 3.1K citations

    30

    h-index

  2. XL
    Xiaoheng Li

    Wenzhou Medical University, China

    25 publications · 678 citations

    18

    h-index

  3. QL
    Qingquan Lian

    Wenzhou Medical University, China

    21 publications · 695 citations

    17

    h-index

  4. XC
    Xianwu Chen

    Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, China

    16 publications · 582 citations

    16

    h-index

  5. YW
    Yiyan Wang

    Wenzhou Medical University, China

    22 publications · 557 citations

    16

    h-index

1–5 of 2.5K

Institutions

718

  1. Population Council

    New York, United States

    26 h-index

    76 publications

    6.4K citations

  2. Wenzhou Medical University

    Wenzhou, China

    26 h-index

    556 publications

    15.3K citations

  3. Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University

    Wenzhou, China

    23 h-index

    513 publications

    13.6K citations

  4. MRC Centre for Reproductive Health

    Edinburgh, United Kingdom

    21 h-index

    71 publications

    8K citations

  5. University of Turku

    Turku, Finland

    21 h-index

    69 publications

    5.1K citations

  6. Johns Hopkins University

    Baltimore, United States

    19 h-index

    84 publications

    6.5K citations

  7. Inserm

    Paris, France

    17 h-index

    87 publications

    6.1K citations

  8. Utrecht University

    Utrecht, The Netherlands

    17 h-index

    57 publications

    3K citations

1–8 of 718

Venues

  1. Endocrinology

    61 publications · 4.7K citations

    39

    h-index

  2. Biology of Reproduction

    52 publications · 4.2K citations

    38

    h-index

  3. Molecular and Cellular Endocrinology

    32 publications · 1.2K citations

    22

    h-index

  4. PubMed

    Repository · 26 publications · 731 citations

    16

    h-index

  5. Cell and Tissue Research

    18 publications · 1.3K citations

    15

    h-index

1–5