Concepedia

Lead-enzyme Interactions

Lead-Enzyme Interactions is a biochemical phenomenon characterized by the selective binding of lead ions to active sites or functional groups of enzymes, thereby disrupting their catalytic activity and structural integrity through competitive or allosteric inhibition mechanisms.

80

Publications

3.1K

Citations

277

Authors

112

Institutions

Publications per year

2017–2026

7

Parents

Publications

80

Reexamination of Lead(II) Coordination Preferences in Sulfur-Rich Sites:  Implications for a Critical Mechanism of Lead Poisoning

John S. Magyar, Tsu‐Chien Weng, Charlotte M. Stern et al. · Journal of the American Chemical Society · 2005 · 230 citations

, , +16

ENZYME INHIBITION BY LEAD UNDER NORMAL URBAN CONDITIONS

Sven Hernberg, J. Nikkanen · The Lancet · 1970 · 183 citations

, , +9

Lead Binding to δ‐Aminolevulinic Acid Dehydratase (ALAD) in Human Erythrocytes

Ingvar A. Bergdahl, Anders Grubb, Andrejs Schütz et al. · Pharmacology & Toxicology · 1997 · 177 citations · Full text

, , +14

Interaction of zinc and lead on δ-aminolevulinate dehydratase

Vincent N. Finelli, David S. Klauder, M.A. Karaffa et al. · Biochemical and Biophysical Research Communications · 1975 · 131 citations

, , +10

Lead Poisoning and the Inactivation of 5-Aminolevulinate Dehydratase as Modeled by the Tris(2-mercapto-1-phenylimidazolyl)hydroborato Lead Complex, {[Tm<sup>Ph</sup>]Pb}[ClO<sub>4</sub>]

B.M. Bridgewater, Gerard Parkin · Journal of the American Chemical Society · 2000 · 120 citations

, , +10

1–5 of 80

Authors

277

  1. TS
    Tadashi Sakai

    University of Miyazaki, Japan

    5 publications · 146 citations

    5

    h-index

  2. KU
    Koichi USHIO

    Birmingham Accident Hospital, United Kingdom

    5 publications · 146 citations

    5

    h-index

  3. SY
    S Yanagihara

    Tohoku University, Japan

    5 publications · 146 citations

    5

    h-index

  4. IA
    Ingvar A. Bergdahl

    Umeå University, Sweden

    3 publications · 257 citations

    3

    h-index

  5. LW
    Lois W. Tice

    National Institutes of Health, United States

    2 publications · 120 citations

    2

    h-index

1–5 of 277

Institutions

112

  1. University of Michigan

    Ann Arbor, United States

    3 h-index

    5 publications

    166 citations

  2. Lund University

    Lund, Sweden

    3 h-index

    7 publications

    875 citations

  3. National Institutes of Health

    Bethesda, United States

    2 h-index

    5 publications

    252 citations

  4. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    7 publications

    364 citations

  5. Shandong University

    Jinan, China

    2 h-index

    7 publications

    280 citations

  6. Universidade Federal de Santa Maria

    Santa Maria, Brazil

    2 h-index

    10 publications

    262 citations

  7. Rutgers, The State University of New Jersey

    New Brunswick, United States

    2 h-index

    5 publications

    75 citations

  8. University of Colorado Boulder

    Boulder, United States

    1 h-index

    1 publications

    15 citations

1–8 of 112

Venues

  1. Occupational and Environmental Medicine

    5 publications · 104 citations

    5

    h-index

  2. PubMed

    Repository · 4 publications · 63 citations

    4

    h-index

  3. Journal of Inorganic Biochemistry

    3 publications · 79 citations

    3

    h-index

  4. Journal of Histochemistry & Cytochemistry

    3 publications · 158 citations

    3

    h-index

  5. Archives of Toxicology

    2 publications · 37 citations

    2

    h-index

1–5