Concepedia

Lead Antibody Selection

Lead Antibody Selection is a methodological framework in antibody screening that identifies the most promising candidate antibody based on predefined efficacy, specificity, and developability criteria for subsequent preclinical and clinical evaluation.

8

Publications

320

Citations

71

Authors

13

Institutions

Publications per year

2017–2026

6

Parents

Publications

8

An<i>in vitro</i>FcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans

Shan Chung, Yuwen Linda Lin, Julien Lafrance‐Vanasse et al. · mAbs · 2019 · 64 citations · Full text

, , +17

Characterization of novel conformation-selective α-synuclein antibodies as potential immunotherapeutic agents for Parkinson's disease

Michael X. Henderson, Dustin J. Covell, Charlotte Hiu-Yan Chung et al. · Neurobiology of Disease · 2019 · 47 citations · Full text

, , +17

Development of Siglec-9 Blocking Antibody to Enhance Anti-Tumor Immunity

Hyeree Choi, Michelle Ho, Opeyemi S. Adeniji et al. · Frontiers in Oncology · 2021 · 46 citations · Full text

, , +17

Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies

Mark C. Julian, Christine C. Lee, Kathryn E. Tiller et al. · Protein Engineering Design and Selection · 2015 · 42 citations · Full text

, , +17

Rapid charge variant analysis of monoclonal antibodies to support lead candidate biopharmaceutical development

Anne Trappe, Florian Füssl, Sara Carillo et al. · Journal of Chromatography B · 2018 · 41 citations

, , +16

1–5 of 8

Authors

71

  1. CA
    Cheryl A. Jones

    University of Georgia, United States

    1 publications · 33 citations

    1

    h-index

  2. KW
    Kathi Williams

    Fairchild Semiconductor (United States), United States

    1 publications · 64 citations

    1

    h-index

  3. SM
    S. Mark Tompkins

    University of Georgia, United States

    1 publications · 33 citations

    1

    h-index

  4. RD
    Roberto Di Niro

    University of Oslo, Norway

    1 publications · 33 citations

    1

    h-index

  5. JS
    Jürgen Schmidt

    Los Alamos National Laboratory, United States

    1 publications · 33 citations

    1

    h-index

1–5 of 71

Institutions

13

  1. University of Pennsylvania

    Philadelphia, United States

    1 h-index

    14 publications

    658 citations

  2. Rensselaer Polytechnic Institute

    Troy, United States

    1 h-index

    7 publications

    294 citations

  3. University College Dublin

    Dublin, Ireland

    1 h-index

    1 publications

    41 citations

  4. University of Georgia

    Athens, United States

    1 h-index

    3 publications

    99 citations

  5. Los Alamos National Laboratory

    Los Alamos, United States

    1 h-index

    3 publications

    99 citations

  6. The Wistar Institute

    Philadelphia, United States

    1 h-index

    9 publications

    414 citations

  7. Dublin City University

    Dublin, Ireland

    1 h-index

    2 publications

    82 citations

  8. University of Wisconsin–Madison

    Madison, United States

    1 h-index

    3 publications

    39 citations

1–8 of 13

Venues

  1. Protein Engineering Design and Selection

    PEDS · 2 publications · 75 citations

    2

    h-index

  2. mAbs

    2 publications · 98 citations

    2

    h-index

  3. Frontiers in Oncology

    1 publications · 46 citations

    1

    h-index

  4. Neurobiology of Disease

    1 publications · 47 citations

    1

    h-index

  5. AIChE Journal

    1 publications · 13 citations

    1

    h-index

1–5