Concepedia

Lanosterol Synthase

Lanosterol Synthase is an enzymatic catalyst in the cholesterol biosynthesis pathway that belongs to the oxidosqualene cyclase family and is distinguished by its specific role in cyclizing 2,3-oxidosqualene into lanosterol, the first tetracyclic sterol intermediate in the pathway.

257

Publications

11.2K

Citations

1.1K

Authors

380

Institutions

Publications per year

2017–2026

43

Variants

OscOxidosqualene-lanosterol Cyclase

Parents

Publications

257

Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats

Katja Nieweg, Hubert Schaller, Frank W. Pfrieger · Journal of Neurochemistry · 2009 · 300 citations

, , +17

Ergosterol Biosynthesis Inhibitors Become Fungicidal when Combined with Calcineurin Inhibitors against <i>Candida albicans</i> , <i>Candida glabrata</i> , and <i>Candida krusei</i>

Chiatogu Onyewu, Jill R. Blankenship, Maurizio Del Poeta et al. · Antimicrobial Agents and Chemotherapy · 2003 · 284 citations · Full text

, , +17

Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol

Bao‐Liang Song, Norman B. Javitt, Russell A. DeBose‐Boyd · Cell Metabolism · 2005 · 282 citations · Full text

, , +13

Phylogenetic and biochemical evidence for sterol synthesis in the bacterium <i>Gemmata obscuriglobus</i>

Ann Pearson, M. Budin, Jochen J. Brocks · Proceedings of the National Academy of Sciences · 2003 · 248 citations · Full text

, , +13

Isolation of an Arabidopsis thaliana gene encoding cycloartenol synthase by functional expression in a yeast mutant lacking lanosterol synthase by the use of a chromatographic screen.

E. J. Corey, S Matsuda, Bonnie Bartel · Proceedings of the National Academy of Sciences · 1993 · 238 citations

, , +16

1–5 of 257

Authors

1.1K

  1. SP
    Seiichi P. T. Matsuda

    Rice University, United States

    21 publications · 1.1K citations

    20

    h-index

  2. MS
    Masaaki Shibuya

    The University of Tokyo, Japan

    13 publications · 711 citations

    12

    h-index

  3. YE
    Yutaka Ebizuka

    The University of Tokyo, Japan

    13 publications · 707 citations

    12

    h-index

  4. TW
    Tung‐Kung Wu

    National Yang Ming Chiao Tung University, Taiwan

    13 publications · 317 citations

    12

    h-index

  5. GB
    Gianni Balliano

    University of Turin, Italy

    11 publications · 285 citations

    11

    h-index

1–5 of 1.1K

Institutions

380

  1. Rice University

    Houston, United States

    15 h-index

    63 publications

    3.1K citations

  2. Harvard University

    Cambridge, United States

    13 h-index

    47 publications

    4.1K citations

  3. National Yang Ming Chiao Tung University

    Hsinchu, Taiwan

    12 h-index

    63 publications

    1.4K citations

  4. The University of Tokyo

    Tokyo, Japan

    12 h-index

    50 publications

    2.9K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    37 publications

    2.6K citations

  6. University of Ljubljana

    Ljubljana, Slovenia

    7 h-index

    13 publications

    528 citations

  7. Niigata University

    Niigata, Japan

    7 h-index

    18 publications

    442 citations

  8. University of Turin

    Turin, Italy

    7 h-index

    28 publications

    909 citations

1–8 of 380

Venues

  1. Journal of the American Chemical Society

    JACS · 16 publications · 958 citations

    15

    h-index

  2. Organic Letters

    OL · 10 publications · 377 citations

    10

    h-index

  3. Journal of Biological Chemistry

    JBC · 9 publications · 450 citations

    9

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 1.1K citations

    8

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 8 publications · 334 citations

    8

    h-index

1–5