Concepedia

Lagging Strand Looping

Lagging Strand Looping is a molecular mechanism in DNA replication wherein the lagging strand forms a looped conformation to enable coordinated synthesis of Okazaki fragments by the DNA polymerase III holoenzyme on the replication fork.

19

Publications

1.9K

Citations

79

Authors

31

Institutions

Publications per year

2017–2026

0

Parents

Publications

19

Telomerase and DNA End Replication: No Longer a Lagging Strand Problem?

Joachim Lingner, Julia Promisel Cooper, Thomas R. Cech · Science · 1995 · 393 citations · Full text

, , +9

Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase

Yu Fu, Hasan Yardimci, David T. Long et al. · Cell · 2011 · 359 citations · Full text

, , +13

Preferential DNA secondary structure mutagenesis in the lagging strand of replication in E. coli

Thuan Q Trinh, Richard R. Sinden · Nature · 1991 · 237 citations

, , +16

A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands

Robert E. Johnson, Roland Klassen, Louise Prakash et al. · Molecular Cell · 2015 · 190 citations · Full text

, , +16

Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis

Samir M. Hamdan, Joseph J. Loparo, Masateru Takahashi et al. · Nature · 2008 · 141 citations · Full text

, , +15

1–5 of 19

Authors

79

  1. JD
    Jack D. Griffith

    University of North Carolina at Chapel Hill, United States

    2 publications · 112 citations

    2

    h-index

  2. AM
    Antoine M. van Oijen

    University of Wollongong, Australia

    2 publications · 500 citations

    2

    h-index

  3. CC
    Charles C. Richardson

    Harvard University, United States

    2 publications · 202 citations

    2

    h-index

  4. TQ
    Thuan Q Trinh

    University of Cincinnati, United States

    1 publications · 237 citations

    1

    h-index

  5. JC
    Johannes C. Walter

    Harvard University, United States

    1 publications · 359 citations

    1

    h-index

1–5 of 79

Institutions

31

  1. Harvard University

    Cambridge, United States

    3 h-index

    13 publications

    2.7K citations

  2. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    2 h-index

    2 publications

    140 citations

  3. University of Michigan

    Ann Arbor, United States

    2 h-index

    6 publications

    210 citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    5 publications

    275 citations

  5. Georgetown University

    Washington, United States

    1 h-index

    2 publications

    108 citations

  6. Georgetown University Medical Center

    Washington, United States

    1 h-index

    2 publications

    108 citations

  7. National Institutes of Health

    Bethesda, United States

    1 h-index

    1 publications

    51 citations

  8. Département Génétique Animale

    Castanet-Tolosan, France

    1 h-index

    5 publications

    130 citations

1–8 of 31

Venues

  1. Journal of Molecular Biology

    JMB · 3 publications · 107 citations

    3

    h-index

  2. Cell

    2 publications · 448 citations

    2

    h-index

  3. Nature

    2 publications · 378 citations

    2

    h-index

  4. Journal of Biological Chemistry

    JBC · 2 publications · 112 citations

    2

    h-index

  5. Biophysical Journal

    2 publications · 70 citations

    2

    h-index

1–5