Concepedia

Ku Protein Complex

Ku Protein Complex is a heterodimeric DNA repair protein complex that belongs to the non-homologous end joining pathway and is distinguished by its ability to bind specifically to double-strand break ends with high affinity, thereby protecting and bridging broken DNA termini during repair.

271

Publications

22.6K

Citations

1.1K

Authors

355

Institutions

Publications per year

2017–2026

33

Variants

Ku Heterodimer

Parents

Publications

271

The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen

Tanya Gottlieb, Stephen P. Jackson · Cell · 1993 · 1.2K citations

, , +14

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

John R. Walker, Richard A. Corpina, Jonathan M. Goldberg · Nature · 2001 · 1.2K citations

, , +14

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

Guillermo E. Taccioli, Tanya Gottlieb, T Blunt et al. · Science · 1994 · 636 citations

, , +16

Mechanism of interaction between Ku protein and DNA.

Tsuneyo Mimori, John Hardin · Journal of Biological Chemistry · 1986 · 489 citations · Full text

, , +17

Ku Recruits the XRCC4-Ligase IV Complex to DNA Ends

Stephanie A. Nick McElhinny, Carey M. Snowden, Joseph McCarville et al. · Molecular and Cellular Biology · 2000 · 390 citations · Full text

, , +17

1–5 of 271

Authors

1.1K

  1. DJ
    David J. Chen

    The University of Texas Southwestern Medical Center, United States

    9 publications · 858 citations

    9

    h-index

  2. WS
    William S. Dynan

    Augusta University, United States

    9 publications · 511 citations

    9

    h-index

  3. BS
    Bernard Salles

    Centre National de la Recherche Scientifique, France

    8 publications · 420 citations

    8

    h-index

  4. MK
    Manabu Koike

    National Institutes for Quantum Science and Technology, Japan

    8 publications · 275 citations

    8

    h-index

  5. SP
    Susan P. Lees‐Miller

    University of Calgary, Canada

    8 publications · 925 citations

    8

    h-index

1–5 of 1.1K

Institutions

355

  1. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    52 publications

    4K citations

  2. Augusta University

    Augusta, United States

    12 h-index

    37 publications

    3K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    11 h-index

    41 publications

    6.8K citations

  4. Harvard University

    Cambridge, United States

    11 h-index

    55 publications

    3.6K citations

  5. National Institutes of Health

    Bethesda, United States

    10 h-index

    21 publications

    3.1K citations

  6. Memorial Sloan Kettering Cancer Center

    New York, United States

    9 h-index

    28 publications

    5.1K citations

  7. Lawrence Berkeley National Laboratory

    Berkeley, United States

    9 h-index

    23 publications

    1.9K citations

  8. The University of Texas Southwestern Medical Center

    Dallas, United States

    9 h-index

    38 publications

    2.7K citations

1–8 of 355

Venues

  1. Journal of Biological Chemistry

    JBC · 45 publications · 4.4K citations

    37

    h-index

  2. Nucleic Acids Research

    27 publications · 1.9K citations

    22

    h-index

  3. Molecular and Cellular Biology

    MCB · 14 publications · 1.7K citations

    14

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 1.2K citations

    10

    h-index

  5. Biochemistry

    8 publications · 401 citations

    8

    h-index

1–5