Concepedia

Kozak Sequence Design

Kozak Sequence Design is a methodological framework in molecular biology that specifies the optimization of nucleotide sequences surrounding the start codon to enhance translational initiation efficiency in eukaryotic expression vector systems.

10

Publications

436

Citations

81

Authors

38

Institutions

Publications per year

2017–2026

6

Parents

Publications

10

Rps26 directs mRNA-specific translation by recognition of Kozak sequence elements

Max Ferretti, Homa Ghalei, Ethan A Ward et al. · Nature Structural & Molecular Biology · 2017 · 175 citations · Full text

, , +14

Dual-isoform hUBE3A gene transfer improves behavioral and seizure outcomes in Angelman syndrome model mice

Matthew C. Judson, Charles Shyng, Jeremy M. Simon et al. · JCI Insight · 2021 · 45 citations · Full text

, , +17

Length of the ORF, position of the first AUG and the Kozak motif are important factors in potential dual-coding transcripts

Heng Xu, Ping Wang, Yujie Fu et al. · Cell Research · 2010 · 42 citations

, , +11

Tailoring translational strength using Kozak sequence variants improves bispecific antibody assembly and reduces product‐related impurities in CHO cells

Noelia Blanco, Ambrose J. Williams, Danming Tang et al. · Biotechnology and Bioengineering · 2020 · 33 citations

, , +17

Co-expression of hepatitis C virus polytope–HBsAg and p19-silencing suppressor protein in tobacco leaves

Sara Mohammadzadeh, Farzin Roohvand, Arash Memarnejadian et al. · Pharmaceutical Biology · 2015 · 31 citations

, , +17

1–5 of 10

Authors

81

  1. YZ
    Yufang Zheng

    Fudan University, China

    1 publications · 42 citations

    1

    h-index

  2. LS
    Lizhen Si

    Chinese Academy of Sciences, China

    1 publications · 42 citations

    1

    h-index

  3. LZ
    Li Zhou

    Chinese Academy of Sciences, China

    1 publications · 42 citations

    1

    h-index

  4. QT
    Quan Tang

    Northwestern Polytechnical University, China

    1 publications · 42 citations

    1

    h-index

  5. TL
    Ting Lan

    Sichuan Agricultural University, China

    1 publications · 26 citations

    1

    h-index

1–5 of 81

Institutions

38

  1. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    26 publications

    884 citations

  2. Scripps Research Institute

    San Diego, United States

    2 h-index

    6 publications

    903 citations

  3. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    2 h-index

    20 publications

    546 citations

  4. University of North Carolina System

    Raleigh, United States

    1 h-index

    1 publications

    45 citations

  5. Janelia Research Campus

    Ashburn, United States

    1 h-index

    1 publications

    45 citations

  6. Kindeva Drug Delivery (United States)

    Saint Paul, United States

    1 h-index

    1 publications

    33 citations

  7. Affiliated Hospital of Southwest Medical University

    Luzhou, China

    1 h-index

    1 publications

    24 citations

  8. National Institute of Genetic Engineering and Biotechnology

    Tehran, Iran

    1 h-index

    1 publications

    31 citations

1–8 of 38

Venues

  1. Biotechnology and Bioengineering

    1 publications · 33 citations

    1

    h-index

  2. 1

    h-index

  3. Nature Structural & Molecular Biology

    1 publications · 175 citations

    1

    h-index

  4. Frontiers in Bioengineering and Biotechnology

    1 publications · 28 citations

    1

    h-index

  5. Nucleic Acids Research

    1 publications · 26 citations

    1

    h-index

1–5