Concepedia

Knowledge-based Pathway Reconstruction

Knowledge-Based Pathway Reconstruction is a computational method in systems biology that integrates curated biological knowledge from established databases and literature to infer, model, or reconstruct biochemical or signaling pathways, distinguishing itself from data-driven approaches by relying primarily on prior expert-validated information rather than on statistical analysis of experimental data.

11

Publications

280

Citations

61

Authors

28

Institutions

Publications per year

2017–2026

3

Parents

Publications

11

Integrated knowledge mining, genome-scale modeling, and machine learning for predicting Yarrowia lipolytica bioproduction

Jeffrey J. Czajka, Tolutola Oyetunde, Yinjie Tang · Metabolic Engineering · 2021 · 64 citations

, , +14

Starch biosynthesis in cassava: a genome-based pathway reconstruction and its exploitation in data integration

Treenut Saithong, Oratai Rongsirikul, Saowalak Kalapanulak et al. · BMC Systems Biology · 2013 · 44 citations · Full text

, , +17

Advances in Computer Methods for Systematic Biology: Artificial Intelligence, Databases, Computer Vision (review)

Dinzhong Ye · Perspectives in biology and medicine · 1994 · 31 citations

, , +10

Analyzing M-CSF dependent monocyte/macrophage differentiation: Expression modes and meta-modes derived from an independent component analysis

Dominik Lutter, Péter Ugocsai, Margot Grandl et al. · BMC Bioinformatics · 2008 · 23 citations · Full text

, , +16

Reconstruction of metabolic pathways by combining probabilistic graphical model-based and knowledge-based methods

Qi Qi, Jilong Li, Jianlin Cheng · BMC Proceedings · 2014 · 22 citations · Full text

, , +17

1–5 of 11

Authors

61

  1. JJ
    Jeffrey J. Czajka

    Washington University in St. Louis, United States

    1 publications · 64 citations

    1

    h-index

  2. JC
    Jianlin Cheng

    University of Missouri, United States

    1 publications · 22 citations

    1

    h-index

  3. JH
    Jörg Hakenberg

    Humboldt-Universität zu Berlin, Germany

    1 publications · 21 citations

    1

    h-index

  4. MA
    Munther A. Dahleh

    Massachusetts Institute of Technology, United States

    1 publications · 15 citations

    1

    h-index

  5. YM
    Yurany Moreno

    Universidad Distrital Francisco José de Caldas, Colombia

    1 publications · 14 citations

    1

    h-index

1–5 of 61

Institutions

28

  1. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    5 publications

    69 citations

  2. Takeda (United States)

    Deerfield, United States

    1 h-index

    1 publications

    64 citations

  3. University of Central Florida

    Orlando, United States

    1 h-index

    1 publications

    14 citations

  4. University of Córdoba

    Montería, Colombia

    1 h-index

    1 publications

    14 citations

  5. University of Regensburg

    Regensburg, Germany

    1 h-index

    7 publications

    161 citations

  6. Politecnico di Torino

    Turin, Italy

    1 h-index

    4 publications

    52 citations

  7. Fundación Universitaria del Área Andina

    Bogotá, Colombia

    1 h-index

    1 publications

    14 citations

  8. King Mongkut's University of Technology Thonburi

    Bangkok, Thailand

    1 h-index

    7 publications

    308 citations

1–8 of 28

Venues

  1. BMC Systems Biology

    1 publications · 44 citations

    1

    h-index

  2. BMC Proceedings

    1 publications · 22 citations

    1

    h-index

  3. Bioinformatics

    1 publications · 17 citations

    1

    h-index

  4. BMC Bioinformatics

    1 publications · 23 citations

    1

    h-index

  5. WORLD SCIENTIFIC eBooks

    Ebook platform · 1 publications · 21 citations

    1

    h-index

1–5