Concepedia

Knock-in Technology

Knock-In Technology is a genetic engineering technique that involves the targeted insertion of a specific exogenous DNA sequence into a precise locus of a genome to enable the controlled expression of a desired gene or mutation within a transgenic organism.

38

Publications

2.1K

Citations

291

Authors

95

Institutions

Publications per year

2017–2026

24

Parents

Publications

38

Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9

Shota Nakade, Takuya Tsubota, Yuto Sakane et al. · Nature Communications · 2014 · 524 citations · Full text

, , +16

Highly efficient genome editing for single-base substitutions using optimized ssODNs with Cas9-RNPs

Sachiko Okamoto, Yasunori Amaishi, Izumi Maki et al. · Scientific Reports · 2019 · 143 citations · Full text

, , +14

Flexible Accelerated STOP Tetracycline Operator-Knockin (FAST): A Versatile and Efficient New Gene Modulating System

Kenji F. Tanaka, Susanne E. Ahmari, E. David Leonardo et al. · Biological Psychiatry · 2010 · 108 citations

, , +11

Ischemia-Induced Neuronal Damage: A Role for Calcium/Calmodulin-Dependent Protein Kinase II

M. Neal Waxham, James C. Grotta, Alcino J. Silva et al. · Journal of Cerebral Blood Flow & Metabolism · 1996 · 102 citations · Full text

, , +17

Precise CRISPR/Cas9 editing of the NHE1 gene renders chickens resistant to the J subgroup of avian leukosis virus

Anna Koslová, Pavel Trefil, Jitka Mucksová et al. · Proceedings of the National Academy of Sciences · 2020 · 97 citations · Full text

, , +17

1–5 of 38

Authors

291

  1. NS
    Naoaki Sakamoto

    Hiroshima University, Japan

    2 publications · 550 citations

    2

    h-index

  2. TS
    Tetsushi Sakuma

    Hiroshima University, Japan

    2 publications · 550 citations

    2

    h-index

  3. TY
    Takashi Yamamoto

    Hiroshima University, Japan

    2 publications · 550 citations

    2

    h-index

  4. SN
    Shota Nakade

    Hiroshima University, Japan

    2 publications · 550 citations

    2

    h-index

  5. KN
    Kazuki Nakamae

    Hiroshima University, Japan

    1 publications · 26 citations

    1

    h-index

1–5 of 291

Institutions

95

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    5 publications

    149 citations

  2. Japan Science and Technology Agency

    Tokyo, Japan

    3 h-index

    5 publications

    156 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    8 publications

    453 citations

  4. Stanford University

    Stanford, United States

    2 h-index

    12 publications

    421 citations

  5. Neurosciences Institute

    La Jolla, United States

    2 h-index

    2 publications

    69 citations

  6. Niigata University

    Niigata, Japan

    2 h-index

    3 publications

    52 citations

  7. Boston Children's Hospital

    Boston, United States

    2 h-index

    3 publications

    98 citations

  8. The Graduate University for Advanced Studies, SOKENDAI

    Hayama, Japan

    2 h-index

    4 publications

    370 citations

1–8 of 95

Venues

  1. Scientific Reports

    5 publications · 321 citations

    5

    h-index

  2. Nature Communications

    3 publications · 565 citations

    3

    h-index

  3. International Journal of Molecular Sciences

    IJMS · 2 publications · 69 citations

    2

    h-index

  4. Development

    2 publications · 78 citations

    2

    h-index

  5. Nucleic Acids Research

    2 publications · 102 citations

    2

    h-index

1–5