Concepedia

Isocratic Separation Optimization

Isocratic Separation Optimization is a methodological framework within chromatographic science that systematically enhances the resolution and efficiency of analyte separation under constant mobile phase composition by optimizing parameters such as flow rate, column temperature, and stationary phase characteristics.

105

Publications

3K

Citations

350

Authors

116

Institutions

Publications per year

2017–2026

16

Parents

Publications

105

Simultaneous selectivity optimization of mobile and stationary phases in reversed-phased liquid chromatography for isocratic separations of phenylthiohydantoin amino acid derivatives

Joseph L. Glajch, Jennifer C. Gluckman, J.G. Charikofsky et al. · Journal of Chromatography A · 1985 · 153 citations

, , +17

Optimization of an isocratic high-performance liquid chromatographic separation of carotenoids

Neal E. Craft, Stephen A. Wise, Joseph H. Soares · Journal of Chromatography A · 1992 · 126 citations

, , +12

Calculating Optimal Modulation Periods to Maximize the Peak Capacity in Two-Dimensional HPLC

Kanta Horie, Hiroshi Kimura, Tohru Ikegami et al. · Analytical Chemistry · 2007 · 108 citations

, , +16

Simple HPLC-UV method for the quantification of metformin in human plasma with one step protein precipitation

Himal Paudel Chhetri, Panna Thapa, Ann Van Schepdael · Saudi Pharmaceutical Journal · 2013 · 94 citations · Full text

, , +17

A critical evaluation of quality criteria for the optimization of chromatographic multicomponent separations

H. J. G. Debets, B. L. Bajema, D.A. Doornbos · Analytica Chimica Acta · 1983 · 75 citations

, , +16

1–5 of 105

Authors

350

  1. DG
    Davy Guillarme

    University of Geneva, Switzerland

    5 publications · 203 citations

    5

    h-index

  2. PJ
    Peter J. Schoenmakers

    University of Amsterdam, Netherlands

    4 publications · 108 citations

    4

    h-index

  3. SF
    Szabolcs Fekete

    University of Geneva, Switzerland

    4 publications · 184 citations

    4

    h-index

  4. JL
    Joseph L. Glajch

    DuPont (United States), United States

    3 publications · 209 citations

    3

    h-index

  5. SE
    Sebastiaan Eeltink

    Vrije Universiteit Brussel, Belgium

    3 publications · 61 citations

    3

    h-index

1–5 of 350

Institutions

116

  1. University of Geneva

    Geneva, Switzerland

    5 h-index

    14 publications

    540 citations

  2. DuPont (United States)

    Wilmington, United States

    4 h-index

    11 publications

    928 citations

  3. Universitat de València

    Valencia, Spain

    4 h-index

    11 publications

    416 citations

  4. University of Lausanne

    Lausanne, Switzerland

    4 h-index

    11 publications

    474 citations

  5. Vrije Universiteit Brussel

    Brussels, Belgium

    4 h-index

    9 publications

    155 citations

  6. University of Groningen

    Groningen, The Netherlands

    3 h-index

    8 publications

    298 citations

  7. University of Amsterdam

    Amsterdam, The Netherlands

    3 h-index

    9 publications

    243 citations

  8. Mansoura University

    Al Mansurah, Egypt

    2 h-index

    8 publications

    100 citations

1–8 of 116

Venues

  1. Journal of Chromatography A

    28 publications · 991 citations

    19

    h-index

  2. Analytical Chemistry

    8 publications · 328 citations

    8

    h-index

  3. 8

    h-index

  4. Journal of Liquid Chromatography

    7 publications · 130 citations

    7

    h-index

  5. Journal of Separation Science

    6 publications · 133 citations

    6

    h-index

1–5