Concepedia

Iron Response Elements

Iron Response Element is a conserved stem-loop RNA structural motif that functions as a cis-regulatory element in the untranslated regions of mRNAs involved in iron metabolism, distinguished by its specific binding to iron regulatory proteins to post-transcriptionally control gene expression in response to cellular iron levels.

490

Publications

40.7K

Citations

1.7K

Authors

530

Institutions

Publications per year

2017–2026

65

Variants

IresIron-responsive Elements

Parents

Publications

490

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

John Casey, Matthias W. Hentze, David M. Koeller et al. · Science · 1988 · 721 citations

, , +15

FIT interacts with AtbHLH38 and AtbHLH39 in regulating iron uptake gene expression for iron homeostasis in Arabidopsis

Youxi Yuan, Huilan Wu, Ning Wang et al. · Cell Research · 2008 · 616 citations

, , +14

Identification of the Iron-Responsive Element for the Translational Regulation of Human Ferritin mRNA

Matthias W. Hentze, S. Wright Caughman, Tracey A. Rouault et al. · Science · 1987 · 576 citations

, , +17

An Iron-responsive Element Type II in the 5′-Untranslated Region of the Alzheimer's Amyloid Precursor Protein Transcript

Jack T. Rogers, Jeffrey Randall, Catherine M. Cahill et al. · Journal of Biological Chemistry · 2002 · 546 citations · Full text

, , +14

A three-hybrid system to detect RNA-protein interactions in vivo.

Dhruba J. SenGupta, Beilei Zhang, Brian C. Kraemer et al. · Proceedings of the National Academy of Sciences · 1996 · 510 citations

, , +16

1–5 of 490

Authors

1.7K

  1. TA
    Tracey A. Rouault

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    37 publications · 5.9K citations

    34

    h-index

  2. MW
    Matthias W. Hentze

    European Molecular Biology Laboratory, Germany

    36 publications · 6.2K citations

    34

    h-index

  3. RD
    Richard D. Klausner

    National Institutes of Health, United States

    26 publications · 5.3K citations

    25

    h-index

  4. JB
    Joe B. Harford

    National Institutes of Health, United States

    23 publications · 4.7K citations

    22

    h-index

  5. KP
    Kostas Pantopoulos

    McGill University, Canada

    21 publications · 1.8K citations

    18

    h-index

1–5 of 1.7K

Institutions

530

  1. National Institutes of Health

    Bethesda, United States

    28 h-index

    120 publications

    16.3K citations

  2. Eunice Kennedy Shriver National Institute of Child Health and Human Development

    Bethesda, United States

    25 h-index

    104 publications

    16.4K citations

  3. Jewish General Hospital

    Montreal, Canada

    17 h-index

    60 publications

    3.6K citations

  4. McGill University

    Montreal, Canada

    17 h-index

    31 publications

    1.9K citations

  5. European Molecular Biology Laboratory

    Heidelberg, Germany

    16 h-index

    61 publications

    11.7K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    56 publications

    6.2K citations

  7. University of Wisconsin–Madison

    Madison, United States

    13 h-index

    49 publications

    3.8K citations

  8. University at Buffalo, State University of New York

    Buffalo, United States

    12 h-index

    30 publications

    1.8K citations

1–8 of 530

Venues

  1. Journal of Biological Chemistry

    JBC · 82 publications · 8.8K citations

    57

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 29 publications · 4.7K citations

    28

    h-index

  3. Nucleic Acids Research

    21 publications · 1.2K citations

    21

    h-index

  4. Journal of Bacteriology

    JB · 17 publications · 1.2K citations

    16

    h-index

  5. Molecular and Cellular Biology

    MCB · 14 publications · 1.5K citations

    14

    h-index

1–5