Concepedia

Ionization Behavior Analysis

Ionization Behavior Analysis is a methodological framework within salt screening that characterizes the acid-base dissociation properties of active pharmaceutical ingredients to predict their solubility, bioavailability, and stability under varying physiological conditions.

492

Publications

21.6K

Citations

1.3K

Authors

336

Institutions

Publications per year

2017–2026

21

Parents

Publications

492

An Extended Table of Hammett Substitutent Constants Based on the Ionization of Substituted Benzoic Acids

Darl H. McDaniel, Herbert C. Brown · The Journal of Organic Chemistry · 1958 · 1.1K citations

, , +11

The Acid Ionization Constant of HOCl from 5 to 35°

John C. Morris · The Journal of Physical Chemistry · 1966 · 920 citations

, , +9

Acid Ionization Constants of Alcohols. II. Acidities of Some Substituted Methanols and Related Compounds<sup>1,2</sup>

P. Ballinger, F. A. Long · Journal of the American Chemical Society · 1960 · 430 citations

, , +8

Pressure dependence of weak acid ionization in aqueous buffers

Robert C. Neuman, Walter Kauzmann, Adam Zipp · The Journal of Physical Chemistry · 1973 · 352 citations

, , +10

Microscopic Protonation Equilibria of Poly(amidoamine) Dendrimers from Macroscopic Titrations

Duško Čakara, Jörg Kleimann, Michal Borkovec · Macromolecules · 2003 · 329 citations

, , +12

1–5 of 492

Authors

1.3K

  1. HS
    Herbert S. Harned

    Yale University, United States

    10 publications · 412 citations

    10

    h-index

  2. FR
    F. Rodante

    Sapienza University of Rome, Italy

    8 publications · 113 citations

    8

    h-index

  3. EJ
    Edward J. King

    University of California, Irvine, United States

    6 publications · 311 citations

    6

    h-index

  4. LG
    Loren G. Hepler

    University of Lethbridge, Canada

    6 publications · 259 citations

    6

    h-index

  5. RM
    R.E. Mesmer

    Oak Ridge National Laboratory, United States

    5 publications · 479 citations

    5

    h-index

1–5 of 1.3K

Institutions

336

  1. University of Lausanne

    Lausanne, Switzerland

    6 h-index

    15 publications

    554 citations

  2. National Institute of Standards and Technology

    Gaithersburg, United States

    5 h-index

    14 publications

    728 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    12 publications

    667 citations

  4. University of Minnesota

    Minneapolis, United States

    5 h-index

    12 publications

    251 citations

  5. University of Illinois Urbana-Champaign

    Urbana, United States

    4 h-index

    17 publications

    1.2K citations

  6. Boston University

    Boston, United States

    4 h-index

    16 publications

    1K citations

  7. University of Miami

    Coral Gables, United States

    4 h-index

    9 publications

    646 citations

  8. University of Cagliari

    Cagliari, Italy

    4 h-index

    21 publications

    423 citations

1–8 of 336

Venues

  1. Journal of the American Chemical Society

    JACS · 95 publications · 4K citations

    33

    h-index

  2. The Journal of Physical Chemistry

    34 publications · 2.4K citations

    20

    h-index

  3. Canadian Journal of Chemistry

    18 publications · 744 citations

    15

    h-index

  4. Journal of Solution Chemistry

    18 publications · 541 citations

    14

    h-index

  5. Journal of Pharmaceutical Sciences

    14 publications · 453 citations

    13

    h-index

1–5