Intrasubject Variability Estimation
Intrasubject Variability Estimation is a statistical method used in bioequivalence assessment to quantify the within-subject variation of pharmacokinetic responses across repeated administrations of a drug product under the same experimental conditions, distinguishing it from intersubject variability estimation by focusing exclusively on the temporal fluctuations within individual subjects rather than differences between subjects.
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13.1K
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970
Authors
404
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2017–2026
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Robert P. Dickson, John R. Erb‐Downward, Christine M. Freeman et al. · Annals of the American Thoracic Society · 2015 · 561 citations · Full text
Fentanyl blood concentration-analgesic response relationship in the treatment of postoperative pain.
G. K. Gourlay, S R Kowalski, J L Plummer et al. · PubMed · 1988 · 266 citations
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University at Buffalo, State University of New York, United States
4 publications · 206 citations
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University of Toronto
Toronto, Canada
6 h-index
13 publications
757 citations

Johns Hopkins University
Baltimore, United States
5 h-index
16 publications
10K citations
University of Michigan
Ann Arbor, United States
5 h-index
12 publications
3.5K citations
University at Buffalo, State University of New York
Buffalo, United States
5 h-index
13 publications
765 citations
University College London
London, United Kingdom
4 h-index
13 publications
411 citations
University of California, Davis
Davis, United States
4 h-index
10 publications
377 citations
Maastricht University
Maastricht, The Netherlands
3 h-index
7 publications
348 citations
Massachusetts Institute of Technology
Cambridge, United States
3 h-index
7 publications
458 citations
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Repository · 24 publications · 1.1K citations
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CPT · 11 publications · 664 citations
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5 publications · 171 citations
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5 publications · 250 citations
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BJCP · 5 publications · 307 citations
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