Concepedia

Interspecies Extrapolation

Interspecies Extrapolation is a modeling framework within physiologically based compartmental modeling that enables the prediction of species-specific toxicological responses by scaling pharmacokinetic and pharmacodynamic parameters across taxa using mechanistic physiological and biochemical covariates.

72

Publications

3.7K

Citations

221

Authors

98

Institutions

Publications per year

2017–2026

10

Parents

Publications

72

Nasal Diagrams: A Tool for Recording the Distribution of Nasal Lesions in Rats and Mice

Stéphane Mery, Elizabeth A. Gross, Donald R. Joyner et al. · Toxicologic Pathology · 1994 · 199 citations · Full text

, , +11

Bayes Methods for Combining the Results of Cancer Studies in Humans and other Species

William DuMouchel, Jeffrey E. Harris · Journal of the American Statistical Association · 1983 · 186 citations

, , +17

Applications and limitations of interspecies scaling and in vitro extrapolation in pharmacokinetics.

Jiunn H. Lin · PubMed · 1998 · 176 citations

, , +15

Relative growth of the limbs and trunk in the African apes

Brian T. Shea · American Journal of Physical Anthropology · 1981 · 171 citations

, , +17

A Critique of the Use of Distribution-Based Extrapolation Models in Ecotoxicology

T.L. Forbes, Valery E. Forbes · Functional Ecology · 1993 · 139 citations

, , +14

1–5 of 72

Authors

221

  1. KT
    Kevin T. Morgan

    Research Triangle Park Foundation, United States

    4 publications · 349 citations

    4

    h-index

  2. JT
    Justin Teeguarden

    Pacific Northwest National Laboratory, United States

    3 publications · 132 citations

    3

    h-index

  3. AM
    Annie M. Jarabek

    Environmental Protection Agency, United States

    3 publications · 147 citations

    3

    h-index

  4. HJ
    Harvey J. Clewell

    The Hamner Institutes for Health Sciences, United States

    3 publications · 152 citations

    3

    h-index

  5. FY
    Frédéric Y. Bois

    Institut national de l'environnement industriel et des risques, France

    3 publications · 119 citations

    3

    h-index

1–5 of 221

Institutions

98

  1. Research Triangle Park Foundation

    Durham, United States

    10 h-index

    23 publications

    1.8K citations

  2. Environmental Protection Agency

    Washington, United States

    7 h-index

    12 publications

    673 citations

  3. Lawrence Berkeley National Laboratory

    Berkeley, United States

    4 h-index

    10 publications

    642 citations

  4. Oak Ridge National Laboratory

    Oak Ridge, United States

    4 h-index

    9 publications

    497 citations

  5. National Center for Environmental Assessment (EPA)

    Cincinnati, United States

    3 h-index

    6 publications

    294 citations

  6. ENVIRON (United States)

    Arlington, United States

    2 h-index

    4 publications

    119 citations

  7. Massachusetts General Hospital

    Boston, United States

    2 h-index

    2 publications

    225 citations

  8. Utrecht University

    Utrecht, The Netherlands

    2 h-index

    4 publications

    120 citations

1–8 of 98

Venues

  1. Environmental Toxicology and Chemistry

    6 publications · 200 citations

    6

    h-index

  2. PubMed

    Repository · 5 publications · 245 citations

    5

    h-index

  3. Inhalation Toxicology

    5 publications · 229 citations

    5

    h-index

  4. Environmental Health Perspectives

    EHP · 5 publications · 232 citations

    5

    h-index

  5. Regulatory Toxicology and Pharmacology

    RTP · 4 publications · 222 citations

    4

    h-index

1–5