Concepedia

Interferon Desensitization

Interferon Desensitization is a biological regulatory mechanism characterized by the attenuated cellular response to interferons following prolonged or repeated exposure, thereby distinguishing it from acute interferon signaling by its adaptive reduction in pathway sensitivity.

9

Publications

442

Citations

60

Authors

27

Institutions

Publications per year

2017–2026

2

Parents

Publications

9

Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction.

Andrew C. Larner, Arijit Chaudhuri, James Darnell · Journal of Biological Chemistry · 1986 · 202 citations · Full text

, , +14

Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction

Frédérique Kok, Marcus Rosenblatt, Melissa Teusel et al. · Molecular Systems Biology · 2020 · 55 citations · Full text

, , +11

Interferon-related mental deterioration and behavioral changes in patients with renal cell carcinoma

Ofer Merimsky, Irith Reider‐Groswasser, Moshe Inbar et al. · European Journal of Cancer and Clinical Oncology · 1990 · 47 citations

, , +16

Safety and Antiviral Activity of Albinterferon Alfa-2b in Prior Interferon Nonresponders With Chronic Hepatitis C

David R. Nelson, Vinod K. Rustgi, Vijayan Balan et al. · Clinical Gastroenterology and Hepatology · 2008 · 40 citations

, , +14

Phorbol Ester-mediated Down-regulation of an Interferon-inducible Gene

Hiroaki Akai, Andrew C. Larner · Journal of Biological Chemistry · 1989 · 26 citations · Full text

, , +14

1–5 of 9

Authors

60

  1. AC
    Andrew C. Larner

    Center for Biologics Evaluation and Research, United States

    2 publications · 228 citations

    2

    h-index

  2. AK
    Ali Kemal Erdemoğlu

    Kırıkkale University, Türkiye

    1 publications · 12 citations

    1

    h-index

  3. SC
    Samario Chaitchik

    Tel Aviv University, Israel

    1 publications · 47 citations

    1

    h-index

  4. HA
    Hiroaki Akai

    Tohoku University, Japan

    1 publications · 26 citations

    1

    h-index

  5. AJ
    Andrew J. Muir

    Duke University, United States

    1 publications · 40 citations

    1

    h-index

1–5 of 60

Institutions

27

  1. GlaxoSmithKline (Netherlands)

    Zeist, Netherlands

    1 h-index

    3 publications

    120 citations

  2. Florida College

    Temple Terrace, United States

    1 h-index

    1 publications

    40 citations

  3. Human Genome Sciences (United States)

    Rockville, United States

    1 h-index

    1 publications

    40 citations

  4. University of Florida

    Gainesville, United States

    1 h-index

    2 publications

    80 citations

  5. Tel Aviv University

    Tel Aviv, Israel

    1 h-index

    4 publications

    188 citations

  6. KU Leuven

    Leuven, Belgium

    1 h-index

    1 publications

    16 citations

  7. Metropolitan Research Institute

    Budapest, Hungary

    1 h-index

    1 publications

    40 citations

  8. Mayo Clinic

    Rochester, United States

    1 h-index

    2 publications

    80 citations

1–8 of 27

Venues

  1. Journal of Biological Chemistry

    JBC · 2 publications · 228 citations

    2

    h-index

  2. eLife

    1 publications · 24 citations

    1

    h-index

  3. Clinical Gastroenterology and Hepatology

    CGH · 1 publications · 40 citations

    1

    h-index

  4. Journal of General Virology

    1 publications · 16 citations

    1

    h-index

  5. Molecular Systems Biology

    1 publications · 55 citations

    1

    h-index

1–5